Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
303/433
Matches for
“hepatic fibrosis”
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Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
…the development and progression of hepatic fibrosis in patients with psoriasis receiving…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation.
…initial to end stage (mild fibrosis to cirrhosis). Although, liver biopsy is…
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Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
…Forty four candidate biomarkers for hepatic fibrosis were identified of which 20…
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Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
…cause of chronic hepatitis and hepatic fibrosis. Liver biopsy, because of its…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
…techniques for the evaluation of hepatic fibrosis with particular attention to cost…
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Non-invasive markers for hepatic fibrosis.
…The lack of accurate, reproducible and easily applied methods for fibrosis assessment…
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Noninvasive evaluation of NAFLD.
…and quantification of steatosis, diagnosis of NASH and staging of hepatic fibrosis.
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Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
…hepatic cirrhosis or fibrosis at young age when accompanied with hepatic siderosis…
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
…FibroTest is an indirect serum marker of hepatic fibrosis. ### Main Outcomes And…
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Noninvasive assessment of portal hypertension in patients with cirrhosis.
…they investigate the development of hepatic fibrosis through the measurement of increased…
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Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
…In this study, we performed a detailed hemodynamic and hepatic assessment to…
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Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
…Noninvasive tests of steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis have been poorly…
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…evaluate the feasibility of noninvasive hepatic investigations in HIV-1-infected children…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…liver fibrosis staging using ARFI LSM. ### Conclusions The degree of hepatic necroinflammatory…
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Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
### Background Hepatic fibrosis is highly prevalent in individuals with Fontan circulation. FibroSure…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection.
…hepatic inflammation or steatosis. This review outlines the methods of fibrosis assessment…
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EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.
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Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
…We hypothesized that specific tests for fibrosis developed for other chronic liver…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…Liver fibrosis was evaluated according to the METAVIR scoring system on a…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…fibrosis. Increased APRI values were only found in subjects with advanced hepatic…
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…Established markers of fibrosis, namely, aspartate transaminase-to-platelet ratio index (APRI…
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Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
…LRE was defined as hepatic decompensation, hepatocellular carcinoma (HCC) or liver-related…
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…been proposed to protect against hepatic fibrosis, but few data are available…
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Diagnosis of fibrosis and cirrhosis. Liver biopsy is not always necessary.
…gold-standard" for diagnosis of hepatic fibrosis and cirrhosis. However, it is…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease.
…Currently, although several non-invasive fibrosis markers have been suggested as alternatives…
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
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Liver fibrosis markers in alcoholic liver disease.
…Serum markers of hepatic fibrosis are divided into direct and indirect. Indirect…
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
…Histopathological staging of liver fibrosis according to the METAVIR scoring system served…
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FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
### Background Noninvasive markers of liver fibrosis have not been extensively studied in…
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Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.
…The Obuchowski measure was assessed taking into account the distribution of fibrosis…
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Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
### Background Steatosis is common in patients with hepatitis C virus (HCV) infection…
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
…assess portal or sinusoidal associated fibrosis. All patients had liver stiffness (using…
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[The scope of clinical applications of noninvasive methods for the assessment of liver fibrosis results of orginial studies in a multi-field hospital].
…the evaluation of hepatic fibrosis are discussed (hepatic elastography, fibrotest, ultrasound dopplerography…
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…evaluate dynamic changes of liver fibrosis and steatosis within 12 mo by…
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Non-invasive diagnosis and follow-up of portal hypertension.
Compensated advanced chronic liver disease (cACLD) describes the spectrum of advanced fibrosis…
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Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
…By histology, the METAVIR fibrosis category score was F1 in 7 cases…
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Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease.
…Race-stratified logistic regression was employed to evaluate risk of high fibrosis…
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Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
…The noninvasive measurement of liver fibrosis using transient elastography and fibrosis marker…
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Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication
…F0=no fibrosis and F1=portal fibrosis; and for clinically significant fibrosis…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…Liver biopsy is considered the gold standard for assessment of fibrosis but…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis.
…In recent years, the development of non-invasive tests of fibrosis allows…
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
…mortality in patients with cystic fibrosis (CF). However, detection of CF-associated…
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Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.
…The extreme variability of the incidence of hepatic fibrosis in the literature…
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
### Background Patients with cystic fibrosis (CF) have a relevant morbidity and mortality…
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
…The only key inclusion criteria was advanced fibrosis (Metavir stage F4) confirmed…
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Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.
…The primary endpoint was improvement or stabilization of the Metavir fibrosis score…
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Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.
…The association between total testosterone and risk of advanced hepatic fibrosis (F3…
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Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
### Background & Aims The reliability of transient elastography (TE) to assess liver fibrosis…
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Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C.
…Patients with moderate-to-severe fibrosis (F2-F3-F4) had hepatic ADC…
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Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.
…biopsy, for the evaluation of hepatic fibrosis in patients with chronic hepatitis…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
### Background And Aim Significant hepatic fibrosis is prognostic of liver morbidity and…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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The non-invasive assessment of hepatic fibrosis.
Hepatic disease accounts for approximately 2 million deaths/year worldwide. Liver fibrosis…
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Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.
Haemophilia is an entity, wherein the HCV infection rate is greater than…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
…FibroTest-ActiTest facilitated the evaluation of both fibrosis and activity.
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
### Background & Aim Fibrosis is an independent predictor of death in nonalcoholic steatohepatitis…
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Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
…diagnostic procedures to evaluate liver fibrosis and improvements in therapy with pangenotypic…
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Evaluation of liver stiffness measurement by fibroscan as compared to liver biopsy for assessment of hepatic fibrosis in children with chronic hepatitis C.
…liver biopsy for assessment of hepatic fibrosis in children with chronic hepatitis…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…Non-invasive biological tests have also been evaluated to assess liver fibrosis…
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…However, to date, diagnostic performances of Enhanced Liver Fibrosis (ELF) test, which…
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Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection.
### Background Accurately staging hepatitis C virus (HCV)-related fibrosis is crucial for…
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The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
### Background Biopsy is the usual gold standard for liver steatosis assessment. The…
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Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
…standard serum marker of fibrosis. ### Results Advanced fibrosis (F2-F4) was present…
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…more complex scores in determining fibrosis stage in 157 patients transplanted for…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
…For identifying clinically significant fibrosis, the platelet count, age-platelet index, aspartate…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…advanced fibrosis (AF): 0.78, any fibrosis (AnF): 0.76, significant fibrosis…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
### Background Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly…
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.
…The combination of both approaches as first-line assessment of liver fibrosis…
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
### Purpose Transient elastography (FibroScan, [TE]) and serum fibrosis markers such as the…
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Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients.
### Background Determining the stage of fibrosis by liver biopsy is important in…
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Finasteride and methadone use and risk of advanced hepatitis C related liver disease.
…a decreased risk of advanced hepatic fibrosis or inflammation in HCV+ males…
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
…for significant liver fibrosis (METAVIR ≥F2), advanced liver fibrosis (≥F3) and cirrhosis…
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.
…The staging of liver fibrosis still represents the most important prognostic problem…
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
### Background And Aims Diagnostic values of FibroTest (FT) for hepatic fibrosis have…
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Noninvasive Assessment of Liver Fibrosis.
…There are two clinically relevant endpoints for the staging of liver fibrosis…
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European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
…non-alcoholic fatty liver disease fibrosis score, and SteatoTest and FibroTest scores…
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
…severity of hepatitis C-related fibrosis. The objective of this study was…
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Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.
### Introduction chronic hepatitis C (CHC) can cause severe complications, including fibrosis and…
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
…hepatic and extrahepatic conditions (e.g. age, patient comorbidities, and fibrosis or…
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
…Liver fibrosis was estimated by Fibroscan^®^ and Fibrotest^®^ . Liver-related and non…
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Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions.
…toxicity - with steatosis and early fibrosis. Inflammatory infiltrates were prominent in the…
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Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.
…For the diagnosis of significant fibrosis by the METAVIR scoring system, the…
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PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
…The prevalence of steatosis and fibrosis was higher in minor G allele…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
### Background Liver fibrosis, now assessed by liver biopsy or using non-invasive…
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Management of the patient with SVR. Review
…in those with more advanced fibrosis. To maximize the health benefits of…
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Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C.
### Objectives Liver fibrosis in chronic hepatitis C is related to sex, age…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…Routine assessment of liver fibrosis was requested by the surveyed physicians mostly…
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Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.
Liver fibrosis and activity indexes were validated in patients infected by hepatitis…
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Reproducibility of blood tests of liver fibrosis in clinical practice.
…of blood test for liver fibrosis: FibroMeter, Fibrotest, APRI and their composites…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
…13.1%) with likely advanced fibrosis and found that over 28% of…
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Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis in a large cohort of patients…
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Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
…nonalcoholic steatohepatitis (NASH) and liver fibrosis. Patients underwent an objective assessment of…
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Hepatic and renal end-organ damage in the Fontan circulation: A report from the Australian and New Zealand Fontan Registry.
…Features suggestive of hepatic fibrosis were observed on ultrasound in 87/143…
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Late presentation of chronic viral hepatitis for medical care: a consensus definition.
…jaundice, hepatic encephalopathy, clinically detectable ascites, variceal bleeding) and/or hepatocellular carcinoma…
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Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.
…The impact of HBV-G on liver fibrosis progression, as assessed by…
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Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study.
### Objectives Fibrotest (FT) and Actitest (AT) are biochemical markers of fibrosis and…
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication
### Background Systematic screening for liver fibrosis in heavy-drinking patients is a…
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Noninvasive diagnosis in alcohol-related liver disease. Review
…gold standard for identifying advanced hepatic fibrosis, but this approach has several…
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…NITs) of liver fibrosis and to assess fibrosis progression over time in…
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Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
…The combined use of FibroScan and FibroTest to evaluate liver fibrosis could…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…The effect of the stages of hepatic fibrosis to diagnose significant fibrosis…
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Effective use of FibroTest to generate decision trees in hepatitis C.
…fibrosis scores in clinical studies and improve our understanding of fibrosis progression.
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Biomarkers for liver disease in urea cycle disorders.
…Liver disease in UCDs may be associated with hepatic inflammation, hepatic fibrosis…
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Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
…Risk factors for fibrosis progression (F0-F1-F2 to F3-F4) and…
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…fibrosis received transient elastography and examinations for serum markers of fibrosis and…
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Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
### Objectives Staging liver fibrosis in chronic viral hepatitis C (HCV) patients is…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease.
…We compared the accuracy of the Enhanced Liver Fibrosis test (ELF), the…
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Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…The prevalence of fibrosis≥F2 was 10% (CHB), 42% (CHC) and 21…
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
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Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
Combinations of tests comprising alpha2-macroglobulin, haptoglobin, apolipoprotein Al, gamma-glutamyltransferase, total…
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An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
…the diagnosis of significant liver fibrosis (Metavir score >or= 2) compared with…
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Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
…Fibrotest and Forns scores were compared with liver fibrosis pathology scored according…
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Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
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Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
…Twenty-eight untreated HCV-related vasculitis patients with severe liver fibrosis (Metavir…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
### Background The prediction of fibrosis is an essential part of the assessment…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
…For the diagnosis of advanced fibrosis, the standardized area under the receiver…
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A novel panel of blood markers to assess the degree of liver fibrosis.
The objective was to develop new blood tests to characterize different fibrosis…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…The third aim was to assess the long-term dynamics of fibrosis…
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Biomarkers of liver fibrosis.
…The mean diagnostic value for the diagnosis of advanced fibrosis assessed using…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…gold standard to assess liver fibrosis in chronic hepatitis C (CHC) and…
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Applicability and variability of liver stiffness measurements according to probe position.
…was used to define advanced fibrosis instead of 8.8 kPa (33…
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Impact of hepatitis C and liver fibrosis on antiretroviral plasma drug concentrations in HIV-HCV co-infected patients: the HEPADOSE study.
…Among the 73 co-infected patients, 27 had a fibrosis score (Fibrotest…
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Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
…However, in the male group, the intensity of liver fibrosis was higher…
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Non-invasive biomarkers of liver fibrosis in haemophilia patients with hepatitis C: can you avoid liver biopsy?
Liver biopsy remains the gold standard for the evaluation of fibrosis despite…
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
…biopsy for the diagnosis of fibrosis in patients with chronic liver disease…
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Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
### Background Non-invasive liver fibrosis scores have been proposed as alternatives to…
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FibroMAX: towards a new universal biomarker of liver disease?
…FibroTest (BioPredictive) for the quantitative assessment of fibrosis; SteatoTest (BioPredictive) for the…
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Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
### Background & Aims Non-invasive assessment of liver fibrosis is a challenging area…
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Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
Non-invasive modalities to estimate fibrosis stage are desirable in hepatitis C…
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Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…However, significant fibrosis could not be excluded by any marker (NPV < 65…
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
### Background & Aims Data on liver fibrosis evolution and its involvement in liver…
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Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
Liver fibrosis (LF) must be assessed before talking treatment decisions in hepatitis…
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Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B.
…The primary outcomes were A2-A3 activity and F2-F4 fibrosis (METAVIR…
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Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
…We asked whether changes in noninvasive markers of fibrosis can predict liver…
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Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
### Background/Aims To compare non-invasive biological liver fibrosis scores, as alternatives…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…and non-invasive quantitative estimate of liver fibrosis reliably predicts advanced fibrosis.
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
### Background/Aims According to guidelines, the histological diagnosis of severe alcoholic steatohepatitis…
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Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients.
…hepatitis C virus (HCV)-related fibrosis, is invasive and prone to complications…
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Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
### Background & Aims Time-dependent statistics have been used to assess liver fibrosis…
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Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
…for the diagnosis of significant fibrosis in chronic hepatitis C (CHC) patients…
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…Non-invasive methods for the diagnosis of liver fibrosis, such as transient…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
### Objective Chronic viral hepatitis B and C cause liver fibrosis, leading to…
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Guidelines for the diagnosis of uncomplicated cirrhosis.
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…tests for liver fibrosis [the Enhanced Liver Fibrosis (ELF™) test (Siemens Healthcare…
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Liver fibrosis in adults with Fontan palliation: Do common screening studies predict disease severity?
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Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.
…with established markers of liver fibrosis and parameters of portal hypertension. ### Methods…
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…for the evaluation of liver fibrosis and cirrhosis. ### Aim To determine the…
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Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
…Few studies investigated noninvasive markers of liver fibrosis in hepatitis C virus…
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Relationship between the Fibrotest and portal hypertension in patients with liver disease.
…12%, moderate fibrosis 17%, cirrhosis 71%). There was a significant correlation between…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
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Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
…therapy in patients with METAVIR fibrosis scores (MFS) of F2 or F3…
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Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
…The fibrosis stage was evaluated on the basis of FibroTest. The values…
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to…
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Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.
### Background Assessment of fibrosis progression in chronic liver disease relies upon non…
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Letter: APRI and FIB-4 do not correlate with Fibrosure in the evaluation of liver fibrosis in hepatitis C patients.
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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
…of serum markers of fibrosis and hepatic inflammation, and safety and tolerability…
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Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.
…FibroTest was used to assess fibrosis degree. A structured questionnaire on coffee…
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Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
### Background Methotrexate (MTX) use is associated with hepatic fibrosis in psoriasis patients…
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Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
Non-invasive biomarkers have gained popularity for estimating fibrosis stage. In our…
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.
### Background The efficiency of transient elastography for the assessment of liver fibrosis…
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The product of triglycerides and glucose as biomarker for screening simple steatosis and NASH in asymptomatic women.
…issue for primary prevention of hepatic disease, the objectives of this study…
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American Association for the Study of the Liver
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Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…standard for assessment of liver fibrosis. Non-invasive markers have been proposed…
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
…As HCV clearance may improve liver outcomes, we assessed hepatic fibrosis and…
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…0.83-0.95) for the diagnosis of advanced fibrosis and 0…
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The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy.
…The heterogeneity of APRI for detecting significant fibrosis was affected by median…
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
### Aim To compare noninvasive methods presently used for steatosis detection and quantification…
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Discordance between biochemical markers of liver activity and fibrosis (Actitest-Fibrotest) and liver biopsy in patients with chronic hepatitis C.
…for the evaluation of hepatic activity and fibrosis in patients with chronic…
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
### Background FibroTest (FT) is the most frequently used serum fibrosis marker and…
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Optimal correlation between different instruments for Fibrotest-Actitest protein measurement in patients with chronic hepatitis C.
…Such discordance is of little clinical consequence for liver fibrosis evaluation in…
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
…Differences between fibrosis stages were calculated by non-parametric analysis. The best…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…The cardiovascular Framingham-risk score was calculated; advanced fibrosis and severe steatosis…
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Assessment of methotrexate hepatotoxicity in psoriasis patients: a prospective evaluation of four serum fibrosis markers.
…However, its use is hampered by the risk of liver fibrosis. ### Aim…
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
### Background Noninvasive methods for liver fibrosis evaluation in chronic liver diseases have…
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The role of the non-invasive serum marker FibroTest-ActiTest in the prediction of histological stage of fibrosis and activity in children with naïve chronic hepatitis B infection.
…FT predicted insignificant fibrosis in 14/23 (61%) patients at a cut…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…Severe fibrosis was predicted when FibroTest was >0.59 or liver stiffness…
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis.
…Liver biopsy is the reference standard for assessment of liver fibrosis. However…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…Thresholds defined for each stage of fibrosis were close to those previously…
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Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
…Patients with severe fibrosis (Metavir F3/F4) had lower serum 25(OH…
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[Prognosis assessment of alcoholic liver disease: how and why?].
…FibroTest(®) or FibroMetre A(®)) or hepatic elastography (FibroScan(®)) may allow diagnosing alcohol…
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An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
…The use of FibroTest (FT) and ActiTest (AT), biomarkers of fibrosis and…
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Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
…Serum HCV RNA and non-invasive markers of fibrosis (FibroTest) were tested…
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Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.
…the necroinflammatory activity or the fibrosis did not differ by more than…
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The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
…The FibroTest in point 0.51 for the diagnosis of fibrosis obtained…
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
…Liver fibrosis was measured with shear wave elastography and FibroTest. The risk…
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Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.
…About 1/3 of carriers have moderate to severe liver fibrosis and…
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
### Aim To compare histological endpoint assessment using noninvasive alternatives to biopsy during…
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Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients.
…Between 15 and 20 years, hepatic structural abnormalities were the only disorder…
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Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.
…performance for fibrosis stage F2 (few septa) vs F1 (fibrosis without septa…
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
### Aim The objective of this study was to evaluate liver fibrosis using…
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Paired biopsies were scored 0 to 6 (modified Ishak score), significant fibrosis…
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
…Mean fibrosis, as measured by SWE liver stiffness and FibroTest™, did not…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages].
…Liver biopsy, traditionally regarded as the gold standard of fibrosis staging, has…
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Noninvasive prediction of fibrosis in patients with chronic hepatitis C.
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Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
…The prevalence of grade I LVDD, fibrosis, mild steatosis, moderate-to-severe…
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
…AUC for Fibrotest was 0.848 in discriminating patients with Ishak fibrosis…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…Among the 2,169 patients who underwent liver biopsy, bridging fibrosis (F2…
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Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis.
…Routine radiologic modalities were found to detect hepatic steatosis accurately, but were…
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Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…ratio index (APRI) in determining hepatic fibrosis and necroinflammatory activity in hemodialysis…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
…CAP being implemented on FibroScan(®) (Echosens, Paris, France), both steatosis and fibrosis…
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Fibrotest-Actitest: the biochemical marker of liver fibrosis--the Israeli experience.
…that allows quantification of liver fibrosis and inflammation. This test has been…
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Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
…In univariate analysis, patients with liver fibrosis had more cardiovascular events and…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
### Background & Aims Patients with chronic hepatitis C virus infection and advanced fibrosis…
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Study on noninvasive laboratory tests for fibrosis in chronic HBV infection and their evaluation.
…The five indices together were able to exclude fibrosis with a negative…
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Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis.
### Background Liver fibrosis is a sign of advanced liver disease and is…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication
FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…
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Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
…The analysis of 924 estimates for the diagnosis of bridging fibrosis, cirrhosis…
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Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
…27% significant serum inflammation, 47% fibrosis (F2F3F4) on LB. The diagnostic value…
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
FibroTest has been validated as a biomarker of fibrosis in patients with…
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.
### Objectives Personalized ranges of liver fibrosis serum biomarkers such as FibroTest or…
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Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered the gold standard for assessing histologic lesions…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…Survival was significantly decreased in patients diagnosed with severe fibrosis, whatever the…
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Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.
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Noninvasive biomarkers FibroTest and ActiTest versus liver biopsy in chronic hepatitis C patients: the Middle East experience.
…LB was evaluated by Metavir score for fibrosis and inflammation. Voluntary blood…
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Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
### Objective Nonalcoholic steatohepatitis (NASH) has become a prominent liver disease in contemporary…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
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Hepatitis B: are non-invasive markers of liver fibrosis reliable?
…a 'biological' approach, based on the quantification of biomarkers of fibrosis in…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis.
### Objectives Extent of liver fibrosis is one of the most important factors…
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Alpha-2-macroglobulin and hepatic fibrosis. Diagnostic interest.
…for detection of cirrhosis or fibrosis among drinkers, particularly in patients without…
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
…Histologic staging of liver fibrosis served as the reference standard. ### Results Liver…
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Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.
### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance…
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Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Review
…Liver fibrosis was assessed using transient elastography (10 cohorts), APRI score (11…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…Non-invasive tests (NITs) are increasingly used to detect fibrosis, but their…
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…Sequential Algorithm for Fibrosis Evaluation (SAFE biopsy); Fibropaca algorithm; Leroy algorithm. ### Aim…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
### Background & Aims Liver stiffness can be measured noninvasively to assess liver fibrosis…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
The recent advent of non-invasive methods for assessment of fibrosis allows…
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Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age.
### Background FibroTest (FT) is a validated biomarker of fibrosis. To assess the…
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Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Transient elastography (TE) is a noninvasive technique to evaluate liver fibrosis. We…
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Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
…for the diagnosis of significant fibrosis in chronic hepatitis C (CHC) patients…
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Assessment of liver fibrosis: noninvasive means.
…For FibroTest, the mean diagnostic value for the diagnosis of advanced fibrosis…
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Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
…The SBA levels were significantly higher in patients with severe fibrosis as…
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Screening studies of transient elastography and FibroTest in the general population - Authors' reply.
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…At 10 years, among the 415 patients with baseline advanced fibrosis, 49…
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The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
…The reference was fibrosis Metavir staging. ### Results Diagnosis of significant fibrosis (Metavir…
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FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest.
…to determine the degree of hepatic fibrosis have been developed. The aims…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
### Background/Aims Non-invasive markers of liver fibrosis have recently been developed…
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Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
### Background Non invasive methods for fibrosis evaluation remain to be validated longitudinally…
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Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
…Our study suggests that serum biomarkers may help to diagnose significant fibrosis…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…Non-invasive tests of liver fibrosis might provide a mechanism for earlier…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.
### Background Studies have demonstrated that coronary artery calcification on one hand and…
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Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.
…serum-based assessment of liver fibrosis is still an important diagnostic challenge…
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Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
…for a risk of liver fibrosis risk in the USA (212,297…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B.
…TE had lower performance than FibroTest for identifying advanced fibrosis in All…
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Clinical applicability of non-invasive markers for liver fibrosis in chronic hepatitis C (Letter)
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Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
### Background There is a clear need for better biomarkers of drug-induced…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.
…Contemporaneous biopsies were blindly assessed using the new steatosis, activity and fibrosis…
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Analytical variability of the Fibrotest proteins.
### Objectives The analytical variability of the Fibrotest (FT) parameters raises the issue…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study.
…Beyond its utility in assessing liver fibrosis, the FibroTest® could be a…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
-
Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus.
…The areas under the ROC curves for the diagnosis of significant fibrosis…
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…A new combination of two complementary blood tests, one targeted for fibrosis…
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Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.
…Within these populations, the diagnostic target, significant fibrosis (Metavir F > or = 2…
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Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: longitudinal validation in a randomized trial.
A liver fibrosis index was recently prospectively validated in a cross-sectional…
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Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study.
…As portal hypertension is related to liver fibrosis, this study aimed to…
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Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
…Discordances of at least two fibrosis stages between FT and LB were…
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FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
…These include FibroTest (BioPredictive) for the quantitative assessment of fibrosis, and ActiTest…
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
…non-invasive markers of METAVIR fibrosis stages from F0 to F4 using…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication
…As waiting for the perfect biomarker for the diagnosis of advanced fibrosis…
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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19.
…with the risk of liver fibrosis, inflammation (NASH), and COVID-19. We…
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Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
### Background Non-invasive liver fibrosis scores such as Hepascore (HS) have been…
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FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients.
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Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
…a fibrosis in 18% of cases for FT (8% severe fibrosis) and…
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Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
…FibroTest for advanced fibrosis: 0.85, 0.83-0.87, P<0…
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
…All four of these tests differentiated the fibrosis stage as determined by…
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Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.
### Background Assessing liver fibrosis is traditionally performed by biopsy, an imperfect gold…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
-
Intermethod calibration of alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) results: application to Fibrotest and Actitest scores.
…been proposed to evaluate liver fibrosis or necro-inflammatory lesions as an…
-
Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
### Background & Aims Fibrosis blood tests have been validated in chronic hepatitis C…
-
The predictive value of Fibrotest vs. APRI for the diagnosis of fibrosis in chronic hepatitis C.
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The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
…A cut-off value
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Role of Non-hepatic Medical Comorbidity and Functional Limitations in Predicting Mortality in Patients with HCV.
### Background Medical comorbidities and functional status limitations are determinants of mortality in…
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La Haute Autorite de Sante (HAS) in France— Diagnosis of uncomplicated cirrhosis (Accessed December 2011)
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Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C.
### Objective Blood tests are usually designed to identify significant fibrosis. We evaluated…
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Real-Time Shear Wave versus Transient Elastography for Predicting Fibrosis: Applicability, and Impact of Inflammation and Steatosis. A Non-Invasive Comparison.
…In patients with non-advanced fibrosis (METAVIR F0F1F2), elasticity values estimated by…
-
Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C.
…Recently, detailed fibrosis classifications for several non-invasive tests have been developed…
-
Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease.
…to determine the stage of fibrosis in non-alcoholic fatty liver disease…
-
Meta-analyses of FibroTest diagnostic value in chronic liver disease.
### Background FibroTest (FT) is a biomarker of liver fibrosis initially validated in…
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Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
### Background FibroTest and elastography have been validated as biomarkers of liver fibrosis…
-
Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…DAAs)), the requirement for a fibrosis score to support DDA reimbursement and…
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Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…All children showed significant liver fibrosis (F3 [n = 3]; F2 [n = 1…
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LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
…gammaglutamyltranspeptidase), and a marker of fibrosis (alpha2-macroglobulin). To increase the specificity…
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Altered serum N-glycomics in chronic hepatitis B patients.
…Liver fibrosis was staged using Ishak score. N-glycan profiles of serum…
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Variability of the area under the receiver operating characteristic curves in the diagnostic evaluation of liver fibrosis markers: impact of biopsy length and fragmentation.
…of each fibrosis stage defining advanced and non-advanced fibrosis. ### Results The…
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…elastography (Fibroscan™) to assess liver fibrosis, vs. liver biopsy, in untreated patients…
-
Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.
…a function of fibrosis stages or diagnostic target (fibrosis cut-off). This…
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Performance of the FibroTest cannot be accurately estimated in nine paediatric patients with advanced fibrosis.
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Optimization and robustness of blood tests for liver fibrosis and cirrhosis.
### Objectives To optimize the performance and feasibility of fibrosis blood tests and…
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
…is often oversimplified as the "hepatic manifestation of the metabolic syndrome," it…
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FibroTest (FT) has similar accuracy for cirrhosis in 'intention-to-diagnose' which is superior to transient elastography (TE) in chronic hepatitis B.
-
Impact of steatosis and inflammation definitions on the performance of NASH tests.
…including 15 cases with significant fibrosis. The simplified definition increased the κ…
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The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.
### Background/Aims The aim was to identify a panel of biomarkers (AshTest…
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The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication
### Background Serum biomarkers of steatosis such as the SteatoTest are recommended for…
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Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…liver fibrosis. ### Methods Five blood tests were compared with Metavir fibrosis (F…
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Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference.
…with significant inflammatory activity or fibrosis (A2orF2) were missed by the current…
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
### Background/Aims To assess prospectively the accuracy of transient elastography (TE, FibroScan…
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Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
…reducing steatosis, NASH or liver fibrosis even after adjustment for gender, BMI…
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[The value of noninvasive serological markers in hepatitis B].
Bloodless methods (serological and imaging) for evaluating hepatic fibrosis constitute a good…
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