Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
232/433
Matches for
“Cirrhosis complications”
-
Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…cirrhosis without complications (F4.1), oesophageal varices (F4.2), and severe complications…
-
Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.
…can cause severe complications, including fibrosis and cirrhosis. Very little is known…
-
Management of the patient with SVR. Review
…SVR benefits are well-recognized with reductions in rates of liver complications…
-
Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…the evaluation of complications in patients with cirrhosis. ### Methods A total of…
-
Noninvasive assessment of portal hypertension in patients with cirrhosis.
Severe portal hypertension is responsible for complications and death. Although measurement of…
-
Non-invasive diagnosis and follow-up of portal hypertension.
…the spectrum of advanced fibrosis/cirrhosis in asymptomatic patients at risk of…
-
Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…In all 171 SVR, cirrhosis regressed in 24/43 patients, but 15…
-
An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
…At 4 years follow-up, 50 complications occurred (survival without complications 93…
-
Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
…cirrhosis without complications (F4.1), esophageal varices (F4.2), and severe complications…
-
Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…cirrhosis. Existing guidelines do not advocate screening for liver related complications amongst…
-
Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
### Background And Aims Markers predicting complications of post-hepatitis C cirrhosis are…
-
Guidelines for the diagnosis of uncomplicated cirrhosis.
-
A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
…FibroTest was a better predictor than biopsy staging for HCV complications, with…
-
Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters?
…1) the presence of cirrhosis has prognostic relevance as it entails a…
-
Personalized management of cirrhosis by non-invasive tests of liver fibrosis.
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
-
Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.
…the degree and occurrence of complications. A prospective follow-up study with…
-
Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…Patients>80 yr (43%) with cirrhosis had nonelevated alanine amino transferase (ALT…
-
Assessment of liver fibrosis: noninvasive means.
Liver biopsy, owing to its limitations and risks, is an imperfect gold…
-
FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication
…the prognostic value of liver complications or death related to liver disease…
-
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics.
…that cirrhosis has developed and that the risk of complications (such as…
-
Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
-
Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…This resulted in twice as many cases of cirrhosis being detected, 2…
-
EASL clinical practical guidelines: management of alcoholic liver disease.
-
Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease.
…steatosis to alcoholic steatohepatitis and cirrhosis. Fatty liver develops in more than…
-
Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…normal ALT. (3) Identification of cirrhosis (95% accuracy) was achieved using a…
-
Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.
…Identifying HIV-infected patients with significant fibrosis or cirrhosis plays an important…
-
Noninvasive evaluation of NAFLD.
…Ultrasonography-based transient elastography can exclude advanced fibrosis and cirrhosis, but its…
-
Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…advanced fibrosis (F≥3), and cirrhosis (F = 4) were 0.901, 0…
-
Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
### Background Excessive alcohol consumption may lead to the development of alcohol-related…
-
Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
-
Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
### Background & Aims The aim of this study was to determine the diagnostic…
-
Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…advanced fibrosis (F≥3), and cirrhosis (F = 4), areas under receiver operating…
-
Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…Among patients with cirrhosis 96% (212/220) achieved sustained virological response 12…
-
EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
-
Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients.
…is invasive and prone to complications. Our aim was to determine the…
-
Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…Fibrotest had the best PPV and NPV for cirrhosis (87% and 90…
-
Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
### Background Liver disease is the third leading cause of mortality in patients…
-
Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
…For the diagnosis of cirrhosis, the area under the receiver operating characteristic…
-
Evaluation of FibroTest-ActiTest in children with chronic hepatitis C virus infection.
FibroTest-ActiTest (FT-AT) has been validated in adults with chronic hepatitis…
-
EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
-
Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis.
Nonalcoholic steatohepatitis (NASH) can lead to complications such as liver failure, cirrhosis…
-
An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
-
The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
…patients with cirrhosis (F4) when compared to those without cirrhosis (F1-F3…
-
Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
### Aim The objective of this study was to evaluate liver fibrosis using…
-
Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
### Background & Aims Liver stiffness (LS) measurement using transient elastography and the FibroTest…
-
Liver fibrosis markers in alcoholic liver disease.
…in identifying advanced fibrosis and cirrhosis, and additionally, Fibrotest was independently associated…
-
Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…of fibrosis predicts liver-related complications and survival. We evaluated the abilities…
-
Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
…probe in the diagnosis of cirrhosis (area under under the receiver operating…
-
Non-invasive markers for hepatic fibrosis.
With great advancements in the therapeutic modalities used for the treatment of…
-
Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
### Background Liver biopsy is an imperfect gold standard for assessing the disease…
-
Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…diagnosis of advanced fibrosis and cirrhosis in chronic liver disease. However, there…
-
The role of the non-invasive serum marker FibroTest-ActiTest in the prediction of histological stage of fibrosis and activity in children with naïve chronic hepatitis B infection.
The aim of this study was to investigate whether the non-invasive…
-
Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
…advanced fibrosis/cirrhosis (F3/F4, 24%), nil-mild (F0/F1, 36%), and…
-
Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
-
Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…patients, hepatomegaly in 10, and cirrhosis in two. Liver stiffness as quantified…
-
Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C.
### Objectives Liver fibrosis in chronic hepatitis C is related to sex, age…
-
Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
-
Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
### Background And Aim Mortality of alcohol-related liver disease (ArLD) is increasing…
-
Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
### Background Hepatitis C virus (HCV) is a major cause of chronic hepatitis…
-
Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
### Aim To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI…
-
Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
Non-invasive modalities to estimate fibrosis stage are desirable in hepatitis C…
-
Noninvasive diagnosis in alcohol-related liver disease. Review
### Background Alcohol-related liver disease (ALD) represents a major cause of death…
-
Non-invasive biomarkers of liver fibrosis in haemophilia patients with hepatitis C: can you avoid liver biopsy?
Liver biopsy remains the gold standard for the evaluation of fibrosis despite…
-
Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
…Liver cirrhosis (TE values > 12.5kPa) was encountered in 23.5% and…
-
Prognostic value of liver fibrosis biomarkers: a meta-analysis.
### Aims And Methods Several serum biomarkers such as FibroTest, aspartate transaminase-platelet…
-
Fibrotest-Actitest: the biochemical marker of liver fibrosis--the Israeli experience.
### Background The Fibrotest-Actitest is a six-parameter scoring system that allows…
-
Relationship between the Fibrotest and portal hypertension in patients with liver disease.
…12%, moderate fibrosis 17%, cirrhosis 71%). There was a significant correlation between…
-
Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication
This review summarizes the methodological aspects of the interpretation of non-invasive…
-
Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
### Objective To determine practices among physicians in Canada for the assessment of…
-
The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.
…F≥2)--15.3% and cirrhosis (F4)--in 8.8%. Insignificant steatosis…
-
Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
…genotype, coinfections, and comorbidities. ### Results Cirrhosis or significant fibrosis (METAVIR score >F2…
-
Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
### Background The only way to diagnose nodular regenerative hyperplasia (NRH) is liver…
-
Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.
### Objective To evaluate the rates of reliable diagnosis of cirrhosis by two…
-
Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.
…disease leading to advanced fibrosis, cirrhosis, and liver cancer. We examined the…
-
[Prognosis assessment of alcoholic liver disease: how and why?].
Alcoholic liver disease (ALD) causes more than 5000 deaths per year in…
-
Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
…Eighty-five patients died, including 42 deaths related to liver complications. The…
-
Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.
…tool for early detection of cirrhosis and may have prognostic value in…
-
European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
### Aims To evaluate the application of the recently proposed recommendations by the…
-
The new paradigm of hepatitis C therapy: integration of oral therapies into best practices.
Emerging data indicate that all-oral antiviral treatments for chronic hepatitis C…
-
Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
### Background Liver stiffness and non-invasive tests predict overall survival in chronic…
-
Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and…
-
Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis.
### Background Liver fibrosis is a sign of advanced liver disease and is…
-
EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.
-
Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…prevalence of advanced fibrosis or cirrhosis was low (<10%) without significant dynamic…
-
Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…periportal, F3 = bridging and F4 = cirrhosis. Histology and the biochemical measurements were…
-
Non-invasive evaluation of liver fibrosis in chronic hepatitis C.
…Liver fibrosis and its end-point cirrhosis are the main causes of…
-
La Haute Autorite de Sante (HAS) in France— Diagnosis of uncomplicated cirrhosis (Accessed December 2011)
-
Hepatitis B: are non-invasive markers of liver fibrosis reliable?
…with high performance for detecting cirrhosis. However, its applicability is lower (80…
-
The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy.
…For cirrhosis, the areas under the SROC curve for APRI, FIB-4…
-
Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
### Background In cardiometabolic disorders, non-alcoholic fatty liver disease is frequent and…
-
FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis.
…The area under the hierarchical summary receiver operating curve for liver cirrhosis…
-
Noninvasive Assessment of Liver Fibrosis.
…with the risk of developing cirrhosis. Liver biopsy, traditionally considered as the…
-
Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
…HA suggested cirrhosis (>46 ng/mL) in 3 of 17 subjects (18…
-
Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
### Background Non invasive methods for fibrosis evaluation remain to be validated longitudinally…
-
Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection.
…complications of the end-stage liver disease such as decompensated cirrhosis and…
-
American Association for the Study of the Liver
-
Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…Regarding cirrhosis, accuracy of Castera algorithm was significantly higher than that of…
-
Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.
Haemophilia is an entity, wherein the HCV infection rate is greater than…
-
Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.
…procedure not free from potential complications. However, several non-invasive diagnostic strategies…
-
Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
-
Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
The aim of this study was to evaluate the diagnostic values of…
-
Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection.
…The prevalence of significant fibrosis and cirrhosis were 51% and 16%, respectively…
-
Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
### Background And Aims Noninvasive models have been developed for fibrosis assessment in…
-
Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
-
EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
-
Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
### Background And Aims The FibroTest (FT) demonstrated excellent diagnostic performance in the…
-
[Hepatitis B virus genotypes and evolutionary markers in chronic HBsAG patients in Bujumbura].
…can lead to serious complications, such as cirrhosis and hepato-cellular carcinoma…
-
Biomarkers for liver disease in urea cycle disorders.
…cycle dysfunction have improved, chronic complications, such as liver disease, have become…
-
Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…25). ### Results TE had the best diagnostic accuracy for detection of cirrhosis…
-
Non-invasive assessment of liver fibrosis: are we ready?
-
Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
### Background & Aims Although methotrexate (MTX) is used in the effective treatment of…
-
An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to…
-
Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.
### Background The efficiency of transient elastography for the assessment of liver fibrosis…
-
Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.
…For the diagnosis of cirrhosis, EFT-F4 performances were greater than those…
-
Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.
-
Liver fibrosis in adults with Fontan palliation: Do common screening studies predict disease severity?
-
Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.
To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…
-
Changes of non-invasive markers and FibroScan values during HCV treatment.
The recent advent of non-invasive methods for assessment of fibrosis allows…
-
Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…The AUROC for the diagnosis of liver cirrhosis was 0.92 (95…
-
A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
### Objectives Precise evaluation of the level of liver fibrosis is recommended in…
-
Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
Non-invasive biomarkers have gained popularity for estimating fibrosis stage. In our…
-
The non-invasive assessment of hepatic fibrosis.
Hepatic disease accounts for approximately 2 million deaths/year worldwide. Liver fibrosis…
-
Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication
### Background Systematic screening for liver fibrosis in heavy-drinking patients is a…
-
Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
### Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common…
-
Comparison of FibroTest-ActiTest with histopathology in demonstrating fibrosis and necroinflammatory activity in chronic hepatitis B and C.
### Aims FibroTest and ActiTest are noninvasive tests used in determining the level…
-
Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
### Background Non-invasive liver fibrosis scores have been proposed as alternatives to…
-
[SWE elastography in assessment of liver fibrosis].
…However, due to its invasiveness and possible complications, less or even non…
-
Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
### Background Progression of recurrent hepatitis C is accelerated in liver transplant recipients…
-
Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
…8%, (209/7,463), including cirrhosis in 0.3% (25/7,463…
-
Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…to detect advanced fibrosis and cirrhosis. However, aspartate aminotransferase levels must be…
-
Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and…
-
Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
…32) were included, all had cirrhosis and 80% had EASL histological definition…
-
Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
…The analysis of 924 estimates for the diagnosis of bridging fibrosis, cirrhosis…
-
Cost effectiveness of fibrosis assessment prior to treatment for chronic hepatitis C patients.
…expensive and carries risks of complications. FibroTest is a non-invasive biomarker…
-
The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.
### Background/Aims The aim was to identify a panel of biomarkers (AshTest…
-
Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
Fontan-associated liver disease (FALD) is a serious complication related to the…
-
The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
### Background Nonalcoholic fatty liver disease (NAFLD) is common in bariatric surgery candidates…
-
Glycogenic hepatopathy.
### Background Glycogenic hepatopathy (GH) is a disorder associated with uncontrolled diabetes mellitus…
-
A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
### Background & Aims Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease associated with…
-
Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
### Background This prospective, monocentric study was designed to assess the efficacy of…
-
Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
Therapeutic options in hepatitis C virus (HCV)-related vasculitis may target the…
-
Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
### Objective The aim of our study was to assess the diagnostic performance…
-
Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients.
### Background Determining the stage of fibrosis by liver biopsy is important in…
-
FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
### Aim To compare histological endpoint assessment using noninvasive alternatives to biopsy during…
-
Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
…indices for liver fibrosis and cirrhosis with transient elastography (TE) in chronic…
-
Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication
-
Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
Hepatitis C virus (HCV) infection is a major cause of chronic liver…
-
Late presentation of chronic viral hepatitis for medical care: a consensus definition.
…by the presence of decompensated cirrhosis (at least one symptom of the…
-
Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
…33%) had severe fibrosis or cirrhosis (Metavir F3-F4). The SBA levels…
-
An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
### Background And Aim To assess the clinical and economic outcomes of non…
-
Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.
…The diagnostic value of Fibrotest in the detection of cirrhosis (F4) was…
-
Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
…It carries both metabolic and liver-specific complications that make its approach…
-
Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…For cirrhosis, complex models had higher AUC values than simple models. ### Conclusions…
-
Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study.
### Background And Aims Primary prevention of variceal bleeding with beta-blockers improves…
-
The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
…Diagnosis of cirrhosis. The most accurate synchronous combination was LSE+FibroMeter, which…
-
Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…in patients with primary biliary cirrhosis (PBC) for the assessment of liver…
-
Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.
### Background Liver biopsy and virological end points are standard references for assessing…
-
PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
### Context Recently, it has been shown that an allele in the adiponutrin…
-
FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
-
Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
…Elastometric thresholds were identified for significant fibrosis and cirrhosis. Combined use of…
-
Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
…For the diagnosis of cirrhosis, the AUROC curves were 0.93, 0…
-
Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…Children present severe fatty liver disease with early cirrhosis. Before enzyme replacement…
-
Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
…for Metavir F ≥ 2) or cirrhosis (SAFE or BA for F4). Therefore…
-
Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
…n = 112) or proven liver cirrhosis (n = 22) were included in the…
-
Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
…65 years, 21% had compensated cirrhosis, and 26% baseline HCV-RNA > 10…
-
Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
### Background Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly…
-
Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
…Fontan circulation may develop liver cirrhosis with its sequelae. Therefore, early detection…
-
Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
### Background And Aims Transient elastography (FibroScan; Echosens, Paris, France) is a novel…
-
Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
…The risk of underestimating significant fibrosis and cirrhosis is however greater in…
-
Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
…LFP was estimated using transition rates (cumulative hazard rate) to cirrhosis (F4…
-
Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication
…F3=many septa, and F4=cirrhosis. Statistical analysis was by logistic regression…
-
Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…diagnosis of significant fibrosis and cirrhosis. Obuchowski's measure showed Fibrometer® (0…
-
Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study.
### Objectives Fibrotest (FT) and Actitest (AT) are biochemical markers of fibrosis and…
-
Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study).
…Although the diagnosis of cirrhosis may rely on non-invasive tests, liver…
-
Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
### Background And Aims We aimed to determine the best algorithms for the…
-
The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
### Background Biopsy is the usual gold standard for liver steatosis assessment. The…
-
Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
### Background Noninvasive methods for liver fibrosis evaluation in chronic liver diseases have…
-
Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C.
…Observed 100% negative predictive values for severe fibrosis and cirrhosis were, respectively…
-
[Biomarkers for liver fibrosis: advances, advantages and disadvantages].
Liver cirrhosis in Mexico is one of the most important causes of…
-
Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
### Background Non-invasive liver fibrosis scores such as Hepascore (HS) have been…
-
Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…As a consequence, portal hypertension, cirrhosis, and hepatic failure may develop. So…
-
HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
Acute hepatitis C virus infection remains a major health concern in human…
-
Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
…For the diagnosis of cirrhosis using LCM, SWE specificities were all equal…
-
Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups.
…The median estimated duration of infection for progression to cirrhosis was 30…
-
Guidelines for the screening, care and treatment of persons with hepatitis C infection Key publication
-
Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
### Background/Aims The hepatitis C virus (HCV) infection is important cause of…
-
Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
…cause liver fibrosis, leading to cirrhosis. Fibrosis assessment is essential to establish…
-
Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…FIB4, Fibrotest, Hepascore, FibroMeter) or cirrhosis (CirrhoMeter) were included. Significant liver-related…
-
Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C.
### Unlabelled Liver biopsy is the gold standard for assessing fibrosis but has…
-
Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
### Background Patients with cystic fibrosis (CF) have a relevant morbidity and mortality…
-
Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
### Background & Aims Noninvasive tests (NITs) of liver fibrosis have been suggested to…
-
FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
### Background Noninvasive markers of liver fibrosis have not been extensively studied in…
-
Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.
### Background And Aims The PGAA index was one of the first composite…
-
Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered the gold standard for assessing histologic lesions…
-
Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
### Background/Aims Non-invasive markers of liver fibrosis have recently been developed…
-
External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B.
…patients, 191 (5.4%) with cirrhosis, with at least 1 year of…
-
Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
### Background The prediction of fibrosis is an essential part of the assessment…
-
Non-invasive diagnosis of hepatitis B virus-related cirrhosis.
…Twenty-three percent of patients with CHB progress naturally to liver cirrhosis…
-
Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
### Background/Aims To compare non-invasive biological liver fibrosis scores, as alternatives…
-
Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
### Background HIV-monoinfected individuals are at high risk of nonalcoholic fatty liver…
-
Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
…for diagnosing severe fibrosis and cirrhosis and for excluding significant fibrosis in…
-
FibroMAX: towards a new universal biomarker of liver disease?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
-
Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
### Background & Aims Therapeutic options for patients failing hepatitis C retreatment are limited…
-
Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
### Introduction Recently, a study showed that Controlled Attenuation Parameter (CAP), evaluated with…
-
Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
### Background And Aims Despite the high prevalence of chronic hepatitis B (CHB…
-
Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…AUROC for cirrhosis (F4) was 0.97 for TE followed by FIB…
-
Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.
### Background The efficacy of a maintenance therapy in non-responder patients with…
-
Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
### Background Noninvasive tests are crucial for the management and follow-up of…
-
Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B.
### Background Aims Liver biopsy is the gold standard for assessing hepatitis B…
-
The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…to diagnose significant fibrosis and cirrhosis (≥F2 and F4 respectively) was investigated…
-
A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation.
…end stage (mild fibrosis to cirrhosis). Although, liver biopsy is still considered…
-
Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
### Introduction Long-term tenofovir disoproxil fumarate (TDF) use has been associated with…
-
Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
-
The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…7% experienced disease progression to cirrhosis, whereas for those with F4 disease…
-
Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
### Background Nocturnal hypoxia, the hallmark of OSA, is a potential contributing factor…
-
Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.
### Introduction Non-invasive, i.e. serum-based assessment of liver fibrosis is…
-
A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease.
BACKGROUND: Biochemical markers for liver fibrosis (FibroTest) and necroinflammatory features (ActiTest) are…
-
Biomarkers of liver fibrosis.
Liver biopsy, due to its limitations and risks, is an imperfect gold…
-
Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
### Objectives : Progressive liver injury is a concern in HIV-infected children exposed…
-
Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
### Importance The long-term implications of hepatotoxic effects in patients with psoriasis…
-
A prospective assessment of an 'a la carte' regimen of PEG-interferon alpha2b and ribavirin combination in patients with chronic hepatitis C using biochemical markers.
In therapy with standard interferon and ribavirin, five independent risk factors (RF…
-
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
The correct identification of patients at increased risk of non-alcoholic steatohepatitis…
-
Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
-
Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19.
In patients with non-alcoholic fatty liver disease (NAFLD) with or without…
-
Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
Combinations of tests comprising alpha2-macroglobulin, haptoglobin, apolipoprotein Al, gamma-glutamyltransferase, total…
-
Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…0.76, cirrhosis: 0.72; FIB-4: cirrhosis: 0.83, AF: 0…
-
Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
### Background Steatosis is common in patients with hepatitis C virus (HCV) infection…
-
Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.
### Background Mortality related to complications of cirrhosis is increasing in patients with…
-
Optimal correlation between different instruments for Fibrotest-Actitest protein measurement in patients with chronic hepatitis C.
### Objectives Combination of alpha 2-macroglobulin, haptoglobin, apolipoprotein-A1, gamma-glutamyl transpeptidase…
-
Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes.
### Objective There is a controversy about the performance of blood tests for…
-
Ministère des Affaires Sociales et de la Santé Key publication
-
Silymarin in non alcoholic fatty liver disease.
### Aim This study was undertaken to evaluate the hepatic effects of silybum…
Showing the full result list. The page is server-rendered and not paginated.