Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
176/433 Publications
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
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Toward non-invasive assessment strategies in autoimmune hepatitis.
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Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
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Pharmacotherapeutic efficacy on noninvasive fibrosis progression in nonalcoholic fatty liver disease: a systematic review and network meta-analysis. Review
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
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Response to: Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications, by Jerome Boursier et al.
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Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD.
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Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
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Non-invasive diagnosis and follow-up of portal hypertension.
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
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Biomarkers for liver disease in urea cycle disorders.
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
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Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Review
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
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The non-invasive assessment of hepatic fibrosis.
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Defining the Minimum Acceptable Diagnostic Accuracy of Noninvasive Fibrosis Testing in Cirrhosis: A Decision Analytic Modeling Study.
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Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
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Noninvasive diagnosis in alcohol-related liver disease. Review
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Phase 3, Multicenter Open-Label study to investigate the efficacy of elbasvir and grazoprevir fixed-dose combination for 8 weeks in treatment-naïve, HCV GT1b-infected patients, with non-severe fibrosis.
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Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
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Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease.
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Diagnostic accuracy of the Coopscore© to predict liver fibrosis in human immunodeficiency virus/hepatitis B virus co-infection.
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
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Hepatic and renal end-organ damage in the Fontan circulation: A report from the Australian and New Zealand Fontan Registry.
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Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
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Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
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Late presentation of chronic viral hepatitis for medical care: a consensus definition.
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Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
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Screening studies of transient elastography and FibroTest in the general population - Authors' reply.
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Screening studies of transient elastography and FibroTest in the general population.
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
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Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis.
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Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.
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Management of the patient with SVR. Review
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
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Real-Time Shear Wave versus Transient Elastography for Predicting Fibrosis: Applicability, and Impact of Inflammation and Steatosis. A Non-Invasive Comparison.
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B.
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
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[Hepatitis B virus genotypes and evolutionary markers in chronic HBsAG patients in Bujumbura].
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
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Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease.
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Noninvasive Assessment of Liver Fibrosis.
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis.
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Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
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Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis.
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
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[Diagnostic value of FibroTest for liver fibrosis in patients with chronic hepatitis B].
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[SWE elastography in assessment of liver fibrosis].
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Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.
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FibroTest (FT) has similar accuracy for cirrhosis in 'intention-to-diagnose' which is superior to transient elastography (TE) in chronic hepatitis B.
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Hepatitis B: are non-invasive markers of liver fibrosis reliable?
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Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters?
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis.
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
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Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
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[Prognosis assessment of alcoholic liver disease: how and why?].
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[The value of noninvasive serological markers in hepatitis B].
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Commentary: prognostication of chronic hepatitis B - are Fibrotest and Fibroscan the final answers? Authors' reply.
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Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
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Evaluation of liver stiffness measurement by fibroscan as compared to liver biopsy for assessment of hepatic fibrosis in children with chronic hepatitis C.
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
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Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
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Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
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Noninvasive evaluation of NAFLD.
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices.
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
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Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
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Comparison of noninvasive models of fibrosis in chronic hepatitis B.
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
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Diagnostic algorithms for liver fibrosis in hepatitis C: are they ready to avoid liver biopsy?
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EASL clinical practical guidelines: management of alcoholic liver disease.
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EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
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Non-invasive evaluation of liver fibrosis in chronic hepatitis C.
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Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
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Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
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Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients.
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation.
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A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
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Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C.
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
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FibroStic: a large confirmatory study for non-invasive biomarkers accuracy, if correctly interpreted.
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FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate.
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First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
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Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
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Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.
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Non-invasive markers for hepatic fibrosis.
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
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Noninvasive assessment of portal hypertension in patients with cirrhosis.
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
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Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
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Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
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Diagnosis of fibrosis and cirrhosis. Liver biopsy is not always necessary.
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Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study).
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Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
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Non-invasive assessment of liver fibrosis: are we ready?
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.
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Optimization and robustness of blood tests for liver fibrosis and cirrhosis.
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Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
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An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
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Applicability and variability of liver stiffness measurements according to probe position.
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
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Changes of non-invasive markers and FibroScan values during HCV treatment.
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Combination of fibrosis tests: sequential or synchronous?
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Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
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SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.
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The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.
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[The scope of clinical applications of noninvasive methods for the assessment of liver fibrosis results of orginial studies in a multi-field hospital].
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication
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Assessment of liver fibrosis: noninvasive means.
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Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.
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FibroTest has better diagnostic and prognostic values than the aspartate aminotransferase-to-platelet ratio index in patients with chronic hepatitis C.
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Fibroscan and FibroTest/FibroMax to assess liver fibrosis/cirrhosis in patients with chronic HBV and HCV infection in Georgia.
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Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
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Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
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FibroMAX: towards a new universal biomarker of liver disease?
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FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy.
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Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
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Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.
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Diagnostic value of FibroTest with normal serum aminotransferases.
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FibroScan and FibroTest to assess liver fibrosis in HCV with normal aminotransferases.
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Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
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Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.
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Acoustic Radiation Force Impulse Imaging for Diagnosis and Monitoring of Liver Fibrosis in Patients with Hepatitis C: A review of diagnostic accuracy, clinical effectiveness,…
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Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
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Guidelines for the screening, care and treatment of persons with hepatitis C infection Key publication
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