Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
186/433
Matches for
“Fatty liver index”
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Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
…the SteatoTest; the fatty liver index (FLI); regular abdominal ultrasound (AUS); and…
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EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.
### Background Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
The diagnostic utilities of ultrasonography (US), fatty liver index (FLI) and an…
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Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.
…Fatty liver was diagnosed with abdominal ultrasound and liver steatosis was quantified…
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Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
### Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…APRI), fibrosis index-4 (FIB-4), non-alcoholic fatty liver disease fibrosis…
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
Traditionally a disease of hepatologists, nonalcoholic fatty liver disease (NAFLD) has recently…
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
…of non-alcoholic fatty liver disease (NAFLD). Since liver biopsy is invasive…
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European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
…Liver fat content (assessed using proton magnetic resonance spectroscopy), fatty liver index…
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The product of triglycerides and glucose as biomarker for screening simple steatosis and NASH in asymptomatic women.
…As compared versus SteatoTest, NashTest, Fatty liver index, and Algorithm, the TyG…
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Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.
### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance…
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Noninvasive evaluation of NAFLD.
…developing complications of end-stage liver disease. Although it lacks sensitivity, ultrasonography…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
…CAP was significantly correlated with SteatoTest, Fatty Liver Index (FLI), percentage of…
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Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and…
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
### Background Nonalcoholic fatty liver disease (NAFLD) is common in bariatric surgery candidates…
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Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.
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Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease (COPD) and Non-Alcoholic Fatty Liver Disease (NAFLD…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…factors of liver disease, such as non-alcoholic fatty liver disease, hazardous…
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Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…potential contributing factor for nonalcoholic fatty liver disease (NAFLD). NAFLD severity and…
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Fibromax-based nonalcoholic fatty liver disease in chronic obstructive pulmonary disease patients with obstructive sleep apnea: Methodological considerations.
The relationship between nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea…
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Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
### Background HIV-monoinfected individuals are at high risk of nonalcoholic fatty liver…
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Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.
### Unlabelled Physical activity (PA) is commonly recommended for nonalchoholic fatty liver disease…
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PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
…mass index (BMI) and LFC were not associated with liver fibrosis. ### Conclusions…
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Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.
### Objectives The SteatoTest, fatty liver index (FLI) and hepatic steatosis index (HSI…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…of liver morbidity and mortality in non-alcoholic fatty liver disease (NAFLD…
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Impact of steatosis and inflammation definitions on the performance of NASH tests.
…the limitations of similar European (Fatty Liver Inhibition of Progression) and USA…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
### Background In cardiometabolic disorders, non-alcoholic fatty liver disease is frequent and…
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Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
…risk factor for non-alcoholic fatty liver disease (NAFLD) occurrence and progression…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.
…one hand and non-alcoholic fatty liver disease (NAFLD) on the other…
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Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
…Liver biopsy is considered as the gold standard for assessing nonalcoholic fatty…
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication
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Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
…fatty liver disease with liver biopsy, blood fibrosis tests (Nonalcoholic Fatty Liver…
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Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease - authors' reply.
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Editorial: FibroTest to predict liver-related mortality in NAFLD. Should this change the diagnostic algorithm in NAFLD?
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…ELF, ≥10.43; Nonalcoholic Fatty Liver Disease Fibrosis Score, ≥1.80; Fibrotest…
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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
### Background & Aims Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease associated with…
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Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference.
…ActiTest, FIB4, BARD, and nonalcoholic fatty liver disease scores. A combination of…
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
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Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease.
### Background & Aims Although antioxidants have a protective potential in nonalcoholic fatty liver…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic lesions. The…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study.
…Beyond its utility in assessing liver fibrosis, the FibroTest® could be a…
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Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
### Objective Nonalcoholic steatohepatitis (NASH) has become a prominent liver disease in contemporary…
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The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication
### Background Serum biomarkers of steatosis such as the SteatoTest are recommended for…
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Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
…histologic lesions of non-alcoholic fatty liver disease (NAFLD). The aim was…
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FibroMAX: towards a new universal biomarker of liver disease?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
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Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…CHB and its consequences on liver injury compared with CHC and NAFLD…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.
…liver injury are less well validated in non-alcoholic fatty liver disease…
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Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.
### Background & Aims Patients with diabetes are at risk for nonalcoholic fatty liver…
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Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis.
…B virus, nonalcoholic fatty liver disease, alcoholic liver disease, or cholestatic diseases…
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Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…Children present severe fatty liver disease with early cirrhosis. Before enzyme replacement…
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Silymarin in non alcoholic fatty liver disease.
…silybum marianum on non alcoholic fatty liver disease (NAFLD). ### Methods In 72…
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Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
…All patients in the cohort except 1 were managed without a liver…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
### Background Patients with diabetes are at risk for nonalcoholic fatty liver disease…
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Glycogenic hepatopathy.
…GH or for differentiation of this situation from nonalcoholic fatty liver disease.
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Pharmacotherapeutic efficacy on noninvasive fibrosis progression in nonalcoholic fatty liver disease: a systematic review and network meta-analysis. Review
### Background Fibrosis impacts long-term outcomes among patients with nonalcoholic fatty liver…
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The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
…B, alcoholic liver disease, and non-alcoholic fatty liver disease, and were…
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Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions.
### Background Elevation of liver enzymes in rheumatoid arthritis patients treated with tocilizumab…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…Although ultrasound is still accepted as an initial screen for fatty liver…
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.
…the prediction of non-alcoholic liver disease by non-invasive blood tests…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes.
…The secondary aim was to construct an index (SpectrumF3F4-Index) to predict…
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The non-invasive assessment of hepatic fibrosis.
…Liver fibrosis, as the last stage of numerous chronic liver diseases, is…
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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19.
In patients with non-alcoholic fatty liver disease (NAFLD) with or without…
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The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.
### Background The diagnosis of alcoholic liver diseases is based on the history…
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Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
…and metabolic-dysfunction-associated steatotic liver disease (MASLD); however, the underlying mechanisms…
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Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
…were both alcoholic and nonalcoholic fatty liver disease (NAFLD) in 66%, NAFLD…
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…index was 80%, 83%, and 69%, and for the diagnosis of liver…
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Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
…2-diabetes (T2D), obesity, and liver fibrosis (resmetirom) announce the widespread use…
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Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
…UK Biobank with apparently healthy liver participants (middle-aged, n=138,125…
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Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.
…the liver-related prognosis in patients with non-alcoholic fatty liver disease…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Non-invasive markers for hepatic fibrosis.
…The rate of adoption of non-invasive diagnostic tests for liver fibrosis…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…Routine assessment of liver fibrosis was requested by the surveyed physicians mostly…
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Assessment of liver fibrosis: noninvasive means.
…alcoholic (NAFLD) and alcoholic (ALD) fatty liver diseases. This review summarizes the…
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Biomarkers of liver fibrosis.
…C virus (HCV), hepatitis B virus (HBV), hepatitis nonalcoholic fatty liver disease…
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Liver fibrosis markers in alcoholic liver disease.
Alcohol is one of the main factors of liver damage. The evaluation…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease.
…Fatty liver develops in more than 90% of heavy drinkers, however only…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease.
### Background & Aims Alcohol is the leading cause of cirrhosis and liver-related…
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Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
…abdominal ultrasonography, liver biopsy, calculation of body mass index, and biomarker parameters…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.
### Background The efficiency of transient elastography for the assessment of liver fibrosis…
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
Changes in the liver and bile ducts observed in patients diagnosed with…
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Noninvasive diagnosis in alcohol-related liver disease. Review
…chronic liver diseases such as viral hepatitis and nonalcoholic fatty liver disease…
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Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
…of liver fibrosis in alcoholic patients seems to be the Forns index.
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Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.
…and F3 liver fibrosis stages in non-alcoholic fatty liver disease with…
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FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…index, ultrasound, and Fibroscan. ### Results : Nineteen (>60%) children had signs of liver…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…APRI, Forns'index, Lok index, AST-to-ALT ratio, Fib-4, platelets…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis.
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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Real-Time Shear Wave versus Transient Elastography for Predicting Fibrosis: Applicability, and Impact of Inflammation and Steatosis. A Non-Invasive Comparison.
…Other criteria, elasticity CV, body mass index and depth of measures were…
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Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.
…patients with chronic liver disease or normal liver tissue that surrounded tumors…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication
…CHB), alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD…
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Response to: Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications, by Jerome Boursier et al.
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
…On univariate analysis body mass index (r = 0.40, P = .005) and…
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The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.
…transferrin (CDT%), is confounded by liver disease severity. The aim was to…
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
…Histologic staging of liver fibrosis served as the reference standard. ### Results Liver…
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…markers of liver fibrosis were the body mass index >28 kg/m…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
…Histological features were assessed invasively by liver biopsy and noninvasively using FibroTest…
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Noninvasive Assessment of Liver Fibrosis.
### Background The prognosis and management of chronic liver diseases greatly depend on…
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
…liver fibrosis (FibroScan) > or = 9.5 kPa). A body mass index greater…
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Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
…Further studies are needed to guide strategies for surveillance of liver disease…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication
…of non-invasive biomarkers in liver fibrosis. A scoring system has been…
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Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
…AshTest is an appropriate non-invasive alternative to transjugular liver biopsy.
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[The prevalence of liver and gallbladder pathologies in overweight and obese patients].
…Nonalcoholic fatty liver disease was diagnosed using hepatic elastography and senrum markers…
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A Single Test Combining Blood Markers and Elastography is More Accurate Than Other Fibrosis Tests in the Main Causes of Chronic Liver Diseases.
…liver fibrosis in chronic hepatitis C (CHC) and non-alcoholic fatty liver…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages].
Liver cirrhosis in Mexico is one of the most important causes of…
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Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.
### Aim To assess the diagnostic value of Fibrotest in comparison with liver…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…in order to avoid the liver biopsy currently used for selection of…
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Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
…Liver biopsy, because of its limitations and risks, might be considered an…
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Management of the patient with SVR. Review
…SVR benefits are well-recognized with reductions in rates of liver complications…
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…FS, Fibrotest, FIB-4, aspartate aminotransferase to platelet ratio index (APRI), and…
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…54 ± 11 years) with chronic liver disease and established cirrhosis were included…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
### Background/Aims Non-invasive markers of liver fibrosis have recently been developed…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
### Background And Aims Liver stiffness measurement (LSM) and FibroTest (FT) are frequently…
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Non-invasive assessment of liver fibrosis: are we ready?
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The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
### Background And Aims Blood tests and liver stiffness evaluation (LSE) by ultrasonographic…
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The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
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First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…risk for intestinal failure-associated liver disease (IFALD). The aim of the…
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
### Background Liver disease is the third leading cause of mortality in patients…
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Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease.
…To evaluate the association between anthropometric measurements and advanced liver disease in…
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…The Enhanced Liver Fibrosis (ELF) test consists of an algorithm of three…
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Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
### Background & Aims The reliability of transient elastography (TE) to assess liver fibrosis…
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
…followed for a risk of liver fibrosis risk in the USA (212…
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
…The impact of treatment with ADV vs placebo was assessed on liver…
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Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
…Serum levels of 25(OH)D3 were also significantly correlated with liver…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
### Background Liver fibrosis, now assessed by liver biopsy or using non-invasive…
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The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.
…The use of AshTest may reduce the need for liver biopsy, and…
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication
### Background Systematic screening for liver fibrosis in heavy-drinking patients is a…
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…of liver disease severity. ### Objective To compare the awareness of liver disease…
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
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Biomarkers for liver disease in urea cycle disorders.
…Liver disease in UCDs may be associated with hepatic inflammation, hepatic fibrosis…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
### Background And Aim Mortality of alcohol-related liver disease (ArLD) is increasing…
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…infection or non-HCV-related liver diseases. ### Methods And Results The optimal…
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Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C.
### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B.
…FibroTest, aspartate aminotransferase-platelet ratio index (APRI), FIB4 or TE, with biopsy…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection.
Chronic hepatitis B virus (HBV) infection is a major cause of liver…
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American Association for the Study of the Liver
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…these findings in women and in people with other chronic liver diseases.
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.
The limitations of liver biopsy (invasive procedure, sampling errors, inter-observer variability…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Liver biopsy may be used in patients with suspected ALD to confirm…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation.
…Although, liver biopsy is still considered as gold standard to identify liver…
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
### Introduction Hepatitis C virus (HCV) is the major cause of chronic liver…
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Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
Fontan-associated liver disease (FALD) is a serious complication related to the…
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Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
Serum bile acids (SBAs) are commonly elevated in cholestatic liver diseases, but…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…mass index and co-infection with schistosomiasis may interfere with liver fibrosis…
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
### Background The only way to diagnose nodular regenerative hyperplasia (NRH) is liver…
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
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Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.
…We aimed to verify whether monitoring by liver biopsy might be replaced…
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
…transaminase-platelet ratio index (APRI), FIB-4, and liver stiffness measurement by…
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Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
…These consisted of 29 healthy volunteers and 35 patients with chronic liver…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
### Background Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly…
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
…with chronic liver disease and either histological assessment of liver fibrosis (n…
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
### Background Progression of recurrent hepatitis C is accelerated in liver transplant recipients…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…management of patients with chronic liver disease. Non-invasive tests (NITs) have…
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…Established markers of fibrosis, namely, aspartate transaminase-to-platelet ratio index (APRI…
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Reproducibility of blood tests of liver fibrosis in clinical practice.
### Objectives To evaluate the inter-laboratory reproducibility of blood test for liver…
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Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…a Model for End-Stage Liver Disease score ≥ 10 (24% [14-37…
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Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
…compared with FibroTest (FT) and liver stiffness measurement (LSM) by transient elastography…
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Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection.
### Background And Aims Apolipoprotein A1 (A1) and haptoglobin (HP) serum levels are…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Baseline liver biopsies were obtained (1996-1998) on a random sample of…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
### Background Liver stiffness and non-invasive tests predict overall survival in chronic…
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[Alpha 2 macroglobulin immunoturbidimetric assays (DakoCytomation reagents) on Roche Diagnostic analysers (Modular P, Cobas Integra). Application to FibroTest-Actic-Test].
### Background Alpha2Macroglobulin (A2M) measure showed a revival since it was introduced into…
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…Prevalence of significant liver-fibrosis assessed by TE, ARFI-right-liver-lobe…
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The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
…All patients had a liver biopsy. The Hepascore and FibroTest were calculated…
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Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.
### Unlabelled Males have strikingly increased risk of advanced liver disease. However, the…
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Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
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Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
…better biomarkers of drug-induced-liver-injury (DILI). ### Aims We aimed to…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…METAVIR F stages, body mass index, and platelet count were also independently…
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Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
### Background Liver biopsy is the reference standard for assessing liver fibrosis and…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
…In this case, liver biopsy is still required to properly assess liver…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV.
### Background & Aims The Liver Cancer Risk test algorithm (LCR1-LCR2) is a…
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis.
…Liver biopsy is the reference standard for assessment of liver fibrosis. However…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
…VCTE), and the fibrosis-4 index (FIB-4) and two activity biomarkers…
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External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B.
### Background And Aims The liver cancer risk test (LCR1-LCR2) is a…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…to platelet ratio index, FIB-4), and analyzed liver biopsy samples. We…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis.
### Objectives Extent of liver fibrosis is one of the most important factors…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
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Ministère des Affaires Sociales et de la Santé Key publication
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