Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
170/433
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“fibro test”
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Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
…Compared with FibroTest, Fibro-Nomogram performed slightly better at predicting severe fibrosis…
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
…The combined assessment of ARFI and Fibro-test did not improve the…
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The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.
### Background The diagnosis of alcoholic liver diseases is based on the history…
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Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
…The stability of the samples for each test was studied after storage…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
### Background The prediction of fibrosis is an essential part of the assessment…
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[Alpha 2 macroglobulin immunoturbidimetric assays (DakoCytomation reagents) on Roche Diagnostic analysers (Modular P, Cobas Integra). Application to FibroTest-Actic-Test].
…introduced into FibroTest-ActiTest-Fibro (FT-AT-Fibro) algorithm. More often than…
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
### Importance There is a need for noninvasive tools to monitor hepatotoxicity in…
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Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C.
…of the best-performing blood test outperforms liver biopsy read by a…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation.
…based on simplest routine laboratory test. Genetic marker in combination of imaging…
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
### Background & Aims Although methotrexate (MTX) is used in the effective treatment of…
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
Aim To assess concordance of eight frequently used serology-based scoring indices…
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…APRI-Score, FIB-4 Index, Fibrotest, and ELF-Test were less reliable…
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Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.
…The inter-rater agreement test showed poor agreement between the FT/AT…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.
### Background Liver biopsy and virological end points are standard references for assessing…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
### Background Liver stiffness and non-invasive tests predict overall survival in chronic…
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Liver fibrosis markers in alcoholic liver disease.
Alcohol is one of the main factors of liver damage. The evaluation…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis.
…It is necessary to further improve the test or combine it with…
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
…Data collected included anthropometrics, biochemistry, adiponectin, SteatoTest™, NashTest™, FibroTest™, OWLiver® test and…
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Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…liver biopsy from 56.5 to 0% with the most accurate test.
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Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
…Non invasive Liver FibroScan and Fibro-Test were reliable methods to assess…
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Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Transient elastography (TE) is a noninvasive technique to evaluate liver fibrosis. We…
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Performance of the FibroTest cannot be accurately estimated in nine paediatric patients with advanced fibrosis.
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Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
### Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
The recent advent of non-invasive methods for assessment of fibrosis allows…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.
### Background Studies have demonstrated that coronary artery calcification on one hand and…
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Optimal correlation between different instruments for Fibrotest-Actitest protein measurement in patients with chronic hepatitis C.
### Objectives Combination of alpha 2-macroglobulin, haptoglobin, apolipoprotein-A1, gamma-glutamyl transpeptidase…
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
### Purpose Transient elastography (FibroScan, [TE]) and serum fibrosis markers such as the…
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Appropriate evidence-based data overviews demonstrate the diagnostic and prognostic performances of FibroTest in patients with chronic hepatitis C.
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
### Background & Aims Blood tests and transient elastography (Fibroscan™) have been developed as…
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Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
Liver fibrosis (LF) must be assessed before talking treatment decisions in hepatitis…
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An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
…The testing strategies included a testing algorithm using the Fibrosure test, a…
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
### Purpose To compare the diagnostic performance of acoustic radiation force impulse (ARFI…
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Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.
Haemophilia is an entity, wherein the HCV infection rate is greater than…
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The non-invasive assessment of hepatic fibrosis.
Hepatic disease accounts for approximately 2 million deaths/year worldwide. Liver fibrosis…
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Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
…The NASH FibroSure test can be used to monitor changes in fibrosis…
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Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
Non-invasive biomarkers have gained popularity for estimating fibrosis stage. In our…
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
### Background Preliminary data suggest that performance of non-invasive markers for liver…
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
### Background & Aims Data on liver fibrosis evolution and its involvement in liver…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
### Background Many blood tests have been proposed as alternatives to liver biopsy…
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Noninvasive evaluation of NAFLD.
A common clinical concern in patients with NAFLD is whether they have…
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FibroMAX: towards a new universal biomarker of liver disease?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
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Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.
…activity. ### Conclusion Despite reproducibility of Fibro- and Actitest scores among the six…
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Relationship between the Fibrotest and portal hypertension in patients with liver disease.
### Background The best technique to estimate portal hypertension (PHT) is to measure…
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Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.
…using a non-invasive blood test (FibroTest and ActiTest) was studied in…
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Noninvasive diagnosis in alcohol-related liver disease. Review
…fibrosis, the Enhanced Liver Fibrosis test, FibroTest, and Transient Elastography are the…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
### Objective To determine practices among physicians in Canada for the assessment of…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
### Background Liver fibrosis, now assessed by liver biopsy or using non-invasive…
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
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The role of the non-invasive serum marker FibroTest-ActiTest in the prediction of histological stage of fibrosis and activity in children with naïve chronic hepatitis B infection.
The aim of this study was to investigate whether the non-invasive…
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FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
### Background Noninvasive markers of liver fibrosis have not been extensively studied in…
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FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
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Implementing non-invasive markers for liver fibrosis in clinical practice.
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Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease.
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Intermethod calibration of alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) results: application to Fibrotest and Actitest scores.
Two multi-component scores (Fibrotest and Actitest) have been proposed to evaluate…
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FibroTest is effective in patients with normal transaminases, when accuracy is standardized on fibrosis stage prevalence.
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Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…APRI correlated well with the biopsy. ### Conclusion The FT-AT test does…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered as the gold standard for assessing non…
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
### Background And Aims Noninvasive models have been developed for fibrosis assessment in…
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SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.
### Unlabelled The staging of liver fibrosis is pivotal for defining the prognosis…
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
### Background Acoustic radiation force impulse (ARFI) imaging is a new non-invasive…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
### Background/Aims Non-invasive markers of liver fibrosis have recently been developed…
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The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
### Background Biopsy is the usual gold standard for liver steatosis assessment. The…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
### Background/Aims The hepatitis C virus (HCV) infection is important cause of…
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Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and…
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A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease.
BACKGROUND: Biochemical markers for liver fibrosis (FibroTest) and necroinflammatory features (ActiTest) are…
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Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
Fontan-palliated patients are at risk for the development of Fontan-associated…
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Liver biopsy: the best standard...when everything else fails.
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
### Background Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly…
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The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to…
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First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
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FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest.
…validate a simple, inexpensive, noninvasive test called FIB-4, which combines standard…
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
Acute hepatitis C virus infection remains a major health concern in human…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
### Background Performance of non-invasive fibrosis biomarkers may be influenced by aetiology…
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Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
…The most accurate synchronous combination of FibroScan with a blood test (FibroMeter…
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Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.
…ALT) taken as a control test, were analyzed by latent class method…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…No serological test had predictive value greater than 40% for contemporaneous or…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
### Background/Aims The aim of this study was to compare the performance…
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A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
### Objectives Precise evaluation of the level of liver fibrosis is recommended in…
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Combination of fibrosis tests: sequential or synchronous?
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Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.
Liver stiffness was measured by transient elastography (FibroScan) in 228 consecutive patients…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
### Background & Aims The first aim was to extend the validation of FibroTest…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and…
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
### Aim To compare histological endpoint assessment using noninvasive alternatives to biopsy during…
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LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
### Background No blood test has been shown to be effective in the…
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Meta-analyses of FibroTest diagnostic value in chronic liver disease.
…The aim was to test two hypotheses, one, that the FT diagnostic…
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
### Background This prospective, monocentric study was designed to assess the efficacy of…
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Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.
### Background Mortality related to complications of cirrhosis is increasing in patients with…
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Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
Therapeutic options in hepatitis C virus (HCV)-related vasculitis may target the…
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Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
### Background And Aims Gilbert syndrome (GS) is genotypically predetermined by UGT1A1*28…
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Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions.
### Background Elevation of liver enzymes in rheumatoid arthritis patients treated with tocilizumab…
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Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes.
### Objective There is a controversy about the performance of blood tests for…
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Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
### Objective The aim of our study was to assess the diagnostic performance…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study.
…a non-invasive liver fibrosis test and the progression of lower limb…
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Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients.
…The most useful single test for predicting significant fibrosis was serum alpha…
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Analytical variability of the Fibrotest proteins.
…raises the issue of the test's reliability for routine use. Whereas…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication
FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
Patients infected with hepatitis C virus (HCV) have differing levels of liver…
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.
### Background One of the unmet needs in patients with type 2 diabetes…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
### Background & Aims FibroTest™ (FT) and Transient Elastography (TE) have been validated as…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis.
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages].
Liver cirrhosis in Mexico is one of the most important causes of…
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Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus.
### Background An accurate diagnosis of hepatitis C virus (HCV)-related liver lesions…
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Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.
To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices.
Emerging data indicate that all-oral antiviral treatments for chronic hepatitis C…
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Hepatitis B: are non-invasive markers of liver fibrosis reliable?
Liver biopsy, which was traditionally considered to be the gold standard for…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
The diagnostic utilities of ultrasonography (US), fatty liver index (FLI) and an…
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Retracted: Executive functions in chronic hepatitis C virus infected elderly patients.
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Noninvasive Assessment of Liver Fibrosis.
### Background The prognosis and management of chronic liver diseases greatly depend on…
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Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
In chronic hepatitis C, biopsy is the gold standard for assessment of…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
In Egypt, as elsewhere, liver biopsy (LB) remains the gold standard to…
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Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters?
It is estimated that hepatitis C virus (HCV) infects chronically about 160…
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Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
…cut-offs recommended by the test promoters suggested a fibrosis in 18…
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Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
### Background Hepatic fibrosis is highly prevalent in individuals with Fontan circulation. FibroSure…
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Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
The aim of this study was to evaluate the diagnostic values of…
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
…The most powerful test in predicting fibrosis was ARFI elastography. The diagnostic…
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Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
### Background & Aims Hepatitis C virus (HCV) infection has been shown to be…
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Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
### Aim To assess the performance of several non-invasive markers and of…
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Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
### Background Liver biopsy is considered as the gold standard for assessing nonalcoholic…
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Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
BACKGROUND: Biochemical marker combinations, including alpha2-macroglobulin, haptoglobin, apolipoprotein A1, gamma-glutamyl…
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Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
### Objective And Methods We assessed the reliability of non-invasive biological scoring…
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The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
…synchronous combination of a blood test plus LSE improves the accuracy of…
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Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
### Background & Aims The aim of this study was to determine the diagnostic…
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Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C.
### Unlabelled Liver biopsy is the gold standard for assessing fibrosis but has…
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Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
### Background Non-invasive liver fibrosis scores such as Hepascore (HS) have been…
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Assessment of methotrexate hepatotoxicity in psoriasis patients: a prospective evaluation of four serum fibrosis markers.
…the results of two multi-test algorithms Fibrotest and Hepascore were evaluated…
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Altered serum N-glycomics in chronic hepatitis B patients.
…is a non-invasive blood test for the diagnosis of liver fibrosis…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
### Introduction Recently, a study showed that Controlled Attenuation Parameter (CAP), evaluated with…
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Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data.
### Background Liver biopsy is considered as the gold standard for assessing non…
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
### Background Direct antiviral agents (DAA) showed very good results in terms of…
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Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.
### Background Hepatitis B (HB) infection is common in Mali. However, there is…
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Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
### Background Nocturnal hypoxia, the hallmark of OSA, is a potential contributing factor…
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.
### Background Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
### Background Few data are available on chronic hepatitis C (CHC) in elderly…
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Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.
### Background And Aims The PGAA index was one of the first composite…
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Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease.
### Background Although the FibroTest has been validated as a biomarker to determine…
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Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
…inflammatory cytokines assay, and FibroMax test. ### Results The ACM supplemented group had…
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Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Review
…We found no association between cirrhosis and age, gender, fibrosis test used…
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A novel panel of blood markers to assess the degree of liver fibrosis.
…The AUROC curve for stages F2-F4 in a test combining prothrombin…
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
FibroTest has been validated as a biomarker of fibrosis in patients with…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
### Objective Chronic viral hepatitis B and C cause liver fibrosis, leading to…
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
### Background & Aims Chronic hepatitis C is both a virologic and fibrotic disease…
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…liver biopsy, and evaluate if test combination improves the liver-prognosis assessment…
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[Prognosis assessment of alcoholic liver disease: how and why?].
Alcoholic liver disease (ALD) causes more than 5000 deaths per year in…
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Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C.
…By calculating a specific test for cirrhosis, including the FibroMeter markers, the…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
### Background In cardiometabolic disorders, non-alcoholic fatty liver disease is frequent and…
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication
### Background Systematic screening for liver fibrosis in heavy-drinking patients is a…
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Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
### Background Non invasive methods for fibrosis evaluation remain to be validated longitudinally…
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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
### Background & Aims Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease associated with…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Noninvasive assessment of portal hypertension in patients with cirrhosis.
Severe portal hypertension is responsible for complications and death. Although measurement of…
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Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.
…only as a second line test, i.e., in case of high…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.
…FIB4 and NAFLD scores (Bonferroni test P < 0.05). ### Conclusions In patients…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
### Background Previous research has shown variation in the effects of patient factors…
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Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
### Background FibroTest and elastography have been validated as biomarkers of liver fibrosis…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
…ratio index or FIB-4 test could be utilised for the evaluation…
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Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
**Background/Objectives:** Bariatric surgery (BS), drugs approved for type-2-diabetes (T2D…
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Biomarkers of liver fibrosis.
…FibroTest (FT) was the most studied test with 33 different populations including…
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
### Background & Aim Fibrosis is an independent predictor of death in nonalcoholic steatohepatitis…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…Fibrosis 4 test [FIB4], Enhanced Liver Fibrosis [ELF] test, FibroScan, and FibroTest…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
### Introduction A prognostic model to predict liver severity in people with metabolic…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis.
Chronic hepatitis B (CHB) infection is a major public health problem associated…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Thirty-six scenarios were assessed for each non-invasive test strategy, which…
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Ministère des Affaires Sociales et de la Santé Key publication
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