Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
150/433
Matches for
“alpha-2 macroglobulin”
-
[Alpha 2 macroglobulin immunoturbidimetric assays (DakoCytomation reagents) on Roche Diagnostic analysers (Modular P, Cobas Integra). Application to FibroTest-Actic-Test].
### Background Alpha2Macroglobulin (A2M) measure showed a revival since it was introduced into…
-
Optimal correlation between different instruments for Fibrotest-Actitest protein measurement in patients with chronic hepatitis C.
### Objectives Combination of alpha 2-macroglobulin, haptoglobin, apolipoprotein-A1, gamma-glutamyl transpeptidase…
-
Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
…two dimensional gel electrophoresis (2-DE). This technique separated the proteins in…
-
Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
…be less accurate in type 2 diabetes mellitus (T2DM). We aimed to…
-
Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.
…of 2 years of treatment with peginterferon alpha-2a vs alpha-tocopherol…
-
A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation.
### Background Chronic HCV is one of the major causes of morbidity and…
-
Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…steatosis, perisinusoidal fibrosis, alpha-smooth muscle actin immunoreactivity, (2) quantitative morphometry of…
-
The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…alpha 2 macroglobulin (alpha 2-MG), apolipoprotein A1 (Apo-A1), haptoglobin (Hapto…
-
Alpha-2-macroglobulin and hepatic fibrosis. Diagnostic interest.
Alpha-2-macroglobulin (A2M) is a proteinase inhibitor. Cells synthesizing A2M are…
-
Input of serum haptoglobin fucosylation profile in the diagnosis of hepatocellular carcinoma in patients with non-cirrhotic liver disease.
…haptoglobin, gammaglutamyl-transpeptidase, apolipoproteinA1, alpha-2-macroglobulin) with AFP, AFP-L3, DCP…
-
An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
-
Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19.
…without type 2 diabetes mellitus (T2DM), alpha-2 macroglobulin (A2M), apolipoprotein A1…
-
The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
### Background The Fib-4 index is a simple and inexpensive biomarker to…
-
An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
…For detecting fibrosis stages 2-4 (prevalence 23% [22/95] and 21…
-
Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
…biomarkers. ### Results Five markers (alpha-2-macroglobulin, apolipoprotein-A1, AST, collagen IV…
-
A prospective assessment of an 'a la carte' regimen of PEG-interferon alpha2b and ribavirin combination in patients with chronic hepatitis C using biochemical markers.
…The SVR in genotypes 2 or 3 was 85% (34/40) vs…
-
FibroTest is effective in patients with normal transaminases, when accuracy is standardized on fibrosis stage prevalence.
-
Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…3 kPa for F> or =2, 10.9 kPa and 9.9…
-
A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease.
…glutamyl transpeptidase, alanine aminotransferase, alpha2-macroglobulin, haptoglobin, apolipoprotein A1, and total bilirubin…
-
Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
…of 90.6% (95%CI84.2-95.1) and a specificity of…
-
Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
…Among patients treated for >2.5 years, improvement in MFS or activity…
-
Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…When the 2 groups were pooled together a FT cutoff of 0…
-
Fibrotest-Actitest: the biochemical marker of liver fibrosis--the Israeli experience.
…total bilirubin, gamma-glutamyltransferase, alpha-2 macroglobulin, haptoglobin, alanine aminotransferase, and apolipoprotein…
-
External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV.
…marker of fibrosis (alpha2-macroglobulin) and alpha-fetoprotein (AFP), a specific marker…
-
Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered the gold standard for assessing histologic lesions…
-
Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: longitudinal validation in a randomized trial.
…Seventy-eight patients received 3 MU of IFN-alpha thrice weekly for…
-
Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.
…to mild fibrosis (METAVIR F1-2). Both the AT and FT values…
-
Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age.
…1.97% in P4, 1.77% in HIV centre and 2.61…
-
Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication
…alpha2 macroglobulin, alpha2 globulin (or haptoglobin), gamma globulin, apolipoprotein A1, gamma glutamyltranspeptidase…
-
LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
…To increase the specificity, we then combined (LCR2) these components with alpha…
-
Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…43.9 [40.7-47.2] vs 52.7 [52.2-53…
-
LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis.
…To increase the specificity, we then combined (LCR2) these components with alpha…
-
Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection.
…Similar kinetics of apolipoprotein A1, HP, and alpha-2-macroglobulin were observed…
-
Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
### Background & Objectives One of the multiple factors contributing to virological response in…
-
Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
In chronic hepatitis C, biopsy is the gold standard for assessment of…
-
Changes of non-invasive markers and FibroScan values during HCV treatment.
The recent advent of non-invasive methods for assessment of fibrosis allows…
-
Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients.
…index incorporating age, sex, alpha(2)-macroglobulin, apolipoprotein A1, haptoglobin, bilirubin, and…
-
Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…diagnose significant fibrosis (F > or = 2 by METAVIR) and cirrhosis (F4 by…
-
Comparison of FibroTest-ActiTest with histopathology in demonstrating fibrosis and necroinflammatory activity in chronic hepatitis B and C.
### Aims FibroTest and ActiTest are noninvasive tests used in determining the level…
-
Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
…apoliprotein-A1, haptoglobin and alpha-2-macroglobulin, in patients with DILI. ### Methods…
-
Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B.
…aminotransferases and indices including alpha(2)-macroglobulin, apolipoprotein A1, haptoglobin, gamma-glutamyl…
-
Optimization and robustness of blood tests for liver fibrosis and cirrhosis.
### Objectives To optimize the performance and feasibility of fibrosis blood tests and…
-
Hepatic and renal end-organ damage in the Fontan circulation: A report from the Australian and New Zealand Fontan Registry.
…1.73 m^2^) in 3/131 (2%). Microalbuminuria was detected in…
-
Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication
…for F > or = 2, and 85.7%, 84.2%, 68.6% and…
-
Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
-
External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B.
…marker of fibrosis (alpha2-macroglobulin), and alpha-fetoprotein, a specific marker of…
-
FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
…genotype 2/3 (odds ratio=2.9), fibrosis estimated with FT (4…
-
Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
### Background Non-invasive liver fibrosis scores have been proposed as alternatives to…
-
Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients.
…fibrosis was serum alpha(2)-macroglobulin (cutoff value, 2.52 g/L…
-
Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
**Background/Objectives:** Bariatric surgery (BS), drugs approved for type-2-diabetes (T2D…
-
Guidelines for the diagnosis of uncomplicated cirrhosis.
-
A novel panel of blood markers to assess the degree of liver fibrosis.
…prothrombin index, aspartate aminotransferase, alpha2-macroglobulin (A2M), hyaluronate, urea, and age was…
-
Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
…α2-macroglobulin > 1.92 g/L (area under the receiver operating characteristic…
-
Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
### Background Patients with cystic fibrosis (CF) have a relevant morbidity and mortality…
-
FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
…based therapy for 24 (genotypes 2/3) or 48 (genotype 1) wk…
-
GlycoFibroTest is a highly performant liver fibrosis biomarker derived from DNA sequencer-based serum protein glycomics.
Liver fibrosis is currently assessed by liver biopsy, a costly and rather…
-
Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus.
…negative predictive value of < 0.2 for excluding significant fibrosis was 77…
-
An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
…liver fibrosis (Metavir score >or= 2) compared with liver biopsy. ### Methods We…
-
Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
…Patients had mild (16.2%), moderate (69.9%), or severe (13.9…
-
Effective use of FibroTest to generate decision trees in hepatitis C.
…The FibroTest attributes of age, gender, bilirubin, apolipoprotein, haptoglobin, alpha2 macroglobulin, and…
-
Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.
Haemophilia is an entity, wherein the HCV infection rate is greater than…
-
Evaluation of FibroTest inter-laboratory variations requires standardization on analytical systems and should not be mixed with underpowered histological validation.
-
Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…Eleven of the 33 patients had scores ≤0.2, 6 had significant…
-
Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
…of five biochemical markers (alpha2-macroglobulin, apolipoprotein A1, haptoglobin, total bilirubin, gamma…
-
Biomarkers of liver fibrosis.
Liver biopsy, due to its limitations and risks, is an imperfect gold…
-
Reproducibility of non-invasive fibrosis biomarkers, FibroMeter and FibroTest, could be improved by respecting the analytical standardizations.
-
Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
…CI]: 2.18-6.28) and positive HCV RNA (OR: 2.00…
-
Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
…At a threshold of >5.2 kPa, the sensitivity, specificity, positive and…
-
[Results transferability on RXL, ARX, X-Pand, BN2 (Dade Behring) and modular DP (Roche Diagnostics) analysers: application to component assays of fibrotest and Actitest].
…Disregarding alpha-2 macroglobulin which cannot be assayed on RXL, the results…
-
Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.
…transpeptidase, apolipoprotein A1, and α-2-macroglobulin) scored on a 0-4…
-
Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…pre-selected cut-off thresholds; (2) the influence of potential confounding variables…
-
Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies.
Noninvasive indexes have been developed to predict fibrosis staging. The aim of…
-
The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.
### Background/Aims The aim was to identify a panel of biomarkers (AshTest…
-
Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.
…FibroMeter: 26.1% versus FibroTest: 2.0% (P<10(-3)). The cirrhosis…
-
[Prognosis assessment of alcoholic liver disease: how and why?].
Alcoholic liver disease (ALD) causes more than 5000 deaths per year in…
-
EASL clinical practical guidelines: management of alcoholic liver disease.
-
Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
…Eleven inactive carriers (5.5%) had initial elevated TE values (>7.2…
-
Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.
…Three hundred fifty-two patients who had had 2 interpretable liver biopsies…
-
A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
### Background FibroTest, a noninvasive method of measuring biomarkers of liver fibrosis, is…
-
Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
Combinations of tests comprising alpha2-macroglobulin, haptoglobin, apolipoprotein Al, gamma-glutamyltransferase, total…
-
Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
…The prevalence of presumed fibrosis was 2.8%, (209/7,463), including…
-
Guidelines for the screening, care and treatment of persons with hepatitis C infection Key publication
-
Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…increase in fibrosis, 8 participants; 2-stage, 1; 3-stage, 1). Among…
-
Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
### Background Noninvasive tests are crucial for the management and follow-up of…
-
Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
### Background Many blood tests have been proposed as alternatives to liver biopsy…
-
FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy.
### Background The accurate diagnosis of hepatitis C virus (HCV)-related fibrosis is…
-
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
The correct identification of patients at increased risk of non-alcoholic steatohepatitis…
-
Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
-
Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
…In multivariate analysis AST, GGT and alpha2-macroglobulin had independent predictive power…
-
Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study.
…calcification in individuals with type 2 diabetes (T2D) remains unclear. This study…
-
Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
### Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common…
-
Analytical variability of the Fibrotest proteins.
…haptoglobin, apolipoprotein A1 and alpha2 macroglobulin. The aim of this study was…
-
Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication
-
Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.
### Background One of the unmet needs in patients with type 2 diabetes…
-
Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
-
Impact of hepatitis C and liver fibrosis on antiretroviral plasma drug concentrations in HIV-HCV co-infected patients: the HEPADOSE study.
### Objectives To compare plasma antiretroviral concentrations in HIV-HCV co-infected and…
-
FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
### Background Noninvasive markers of liver fibrosis have not been extensively studied in…
-
Hepatitis B: are non-invasive markers of liver fibrosis reliable?
Liver biopsy, which was traditionally considered to be the gold standard for…
-
Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
…FT score, such as α2-macroglobulin, apolipoprotein A1, haptoglobin, γ-glutamyl transpeptidase…
-
Liver fibrosis markers in alcoholic liver disease.
…combining Prothrombin index (PI), α-2 macroglobulin and hyaluronic acid. Among these…
-
Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…1) significant fibrosis (F>or=2 by METAVIR) was identified with high…
-
The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
…m^2^ to 29.6 ± 4.5 kg/m^2^. Concomitantly, significant…
-
Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
### Background The main causes of liver fibrosis in transfusion-dependent thalassemia major…
-
Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C.
…markers with historical features; and 2) to determine the utility of combining…
-
Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
…Using a cut-off of 5.9 kPa for F ≥ 2 and…
-
Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection.
…n = 4 studies], Forns' [n = 2], FibroTest [n = 1], SHASTA [n = 1…
-
Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
### Background Acoustic radiation force impulse (ARFI) imaging is a new non-invasive…
-
Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
### Background/Aims Non-invasive markers of liver fibrosis have recently been developed…
-
Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
…HBV plasma DNA load ≥3.2 log(10) IU/mL and normal…
-
Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
### Background And Aim Significant hepatic fibrosis is prognostic of liver morbidity and…
-
Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
The aim of this study was to evaluate the diagnostic values of…
-
Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and…
-
Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
### Objective Studies have shown that patients with failing Fontan circulation may develop…
-
Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
…The median patient age was 16.0 years [IQR 14.2], and…
-
Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
…The discordances of the 2 stages were attributed to biopsy failures in…
-
Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
…Repeat TE examinations were conducted 1 and 2 years after study inclusion…
-
Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…By univariate analysis, factors associated with severe fibrosis were age, type 2…
-
Assessment of methotrexate hepatotoxicity in psoriasis patients: a prospective evaluation of four serum fibrosis markers.
…Index PASI 13.5, range 2.2-33) at baseline and weeks…
-
Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…56 years; median BMI, 34.2 kg/m2 [33% with BMI<30…
-
Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.
…Haptoglobin, ALT, gamma GT, alpha-2-macroglobulin, apolipoprotein A1 and bilirubin, required…
-
Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.
### Background & Aims We compared 5 non-specific and 2 specific blood tests…
-
Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…found in 31/79 (39.2%) patients, while abnormal cholestasis parameters in…
-
Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study.
…Among the 92 patients (18%) with 2 fibrosis stages of discordance between…
-
Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…To predict significant fibrosis (F≥2), advanced fibrosis (F≥3), and cirrhosis…
-
Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
…4, 95% CI 1.2-19.2, p<0.02) and low…
-
Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease.
### Background Although the FibroTest has been validated as a biomarker to determine…
-
Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…After 4.2 years median follow-up, 21% had progression of fibrosis…
-
Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
### Objectives : Progressive liver injury is a concern in HIV-infected children exposed…
-
Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
…male gender (Relative Risk=3.29), HIV co-infection (2.33), and…
-
Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
…The median follow-up was 8.2 years. Eighty-five patients died…
-
Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…3% [(24-15) = 9/171); (2.4-9.8%)]. Four cases of…
-
Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease.
Alcoholic liver disease (ALD) consists of a broad spectrum of disorders, ranging…
-
Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…The presence of advanced fibrosis [HR (95% CI)] [2.98 (95% CI…
-
Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.
…risk in individuals with type 2 diabetes (T2D). The primary objective of…
-
Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.
SUMMARY: BACKGROUND: Recent studies strongly suggest that due to the limitations and…
-
Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication
This review summarizes the methodological aspects of the interpretation of non-invasive…
-
Assessment of liver fibrosis: noninvasive means.
…Among a total of 2,237 references, a total of 14 validated…
-
Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…76.2%, P = 0.12). However, SAFE biopsy showed a lower accuracy…
-
Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
The assessment of the fibrotic evolution of chronic hepatitis has always been…
-
Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease.
…made by transient elastography and 2-dimensional shear-wave elastography), and 6…
-
Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
…Endocrinologists and those caring for patients with type 2 diabetes mellitus (T2DM…
-
Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B.
### Background Blood tests and transient elastography (TE), proposed as alternatives to biopsy…
-
Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection.
Chronic hepatitis B virus (HBV) infection is a major cause of liver…
-
FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication
FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…
-
Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.
The limitations of liver biopsy (invasive procedure, sampling errors, inter-observer variability…
-
Non-invasive markers for hepatic fibrosis.
With great advancements in the therapeutic modalities used for the treatment of…
-
Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
…F2 and F1 patients (16.2 ± 10.0 vs. 18.9 ± 8…
-
FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis.
…80 (72-86%), and 6.2% (3.3-11.9), respectively. The…
-
EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
-
Non-invasive diagnosis of hepatitis B virus-related cirrhosis.
Chronic hepatitis B (CHB) infection is a major public health problem associated…
Showing the full result list. The page is server-rendered and not paginated.