Scientific publications for BioPredictive non-invasive diagnostics

Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.

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“FibroTest (FT)”

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  1. Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.

    Park MS et al. · PLoS One · 2013 Match 100

    ### Background And Aims The FibroTest (FT) demonstrated excellent diagnostic performance in the…

    FibroTest HBV

  2. Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.

    Park MS et al. · Liver Int · 2015 Match 100

    …using transient elastography and the FibroTest (FT) are alternatives to liver biopsy…

    FibroTest HBV

  3. Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.

    Kim BK et al. · PLoS One · 2012 Match 100

    ### Background And Aims Diagnostic values of FibroTest (FT) for hepatic fibrosis have…

    FibroTest HBV

  4. Evaluation of FibroTest-ActiTest in children with chronic hepatitis C virus infection.

    Hermeziu B et al. · Gastroenterol Clin Biol · 2010 Match 100

    FibroTest-ActiTest (FT-AT) has been validated in adults with chronic hepatitis…

    ActiTest FibroTest HCV

  5. Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study.

    Halfon P et al. · Am J Gastroenterol · 2006 Match 99

    ### Objectives Fibrotest (FT) and Actitest (AT) are biochemical markers of fibrosis and…

    ActiTest FibroTest HCV

  6. FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication

    Halfon P et al. · Gastroenterol Clin Biol · 2008 Match 99

    FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…

    FibroTest Alcohol HBV HCV +2

  7. Non-invasive biomarkers of liver fibrosis in haemophilia patients with hepatitis C: can you avoid liver biopsy?

    Maor Y et al. · Haemophilia · 2006 Match 99

    …The most thoroughly evaluated biomarker is the FibroTest (FT) (AUROC 0.80…

    FibroTest HCV

  8. Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.

    Maor Y et al. · Haemophilia · 2010 Match 98

    …of significant fibrosis both by Fibrotest (FT) and Fibroscan (FS) in these…

    FibroTest HCV

  9. Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).

    Poynard T et al. · J Hepatol · 2014 Match 98

    …to extend the validation of FibroTest® (FT) and transient elastography (TE) as…

    ActiTest FibroTest HBV

  10. Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.

    Bourliere M et al. · Aliment Pharmacol Ther · 2008 Match 98

    …alternative to liver biopsy and Fibrotest (FT) and propose five optimized combination…

    FibroTest HCV

  11. Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.

    Maor Y et al. · Haemophilia · 2007 Match 97

    …In our hepatitis C-infected haemophilia patients, Fibrotest (FT) correctly identified clinically…

    FibroTest HCV

  12. Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.

    Pokorska-Śpiewak M et al. · Clin Exp Hepatol · 2017 Match 97

    …viral hepatitis using the FibroTest and ActiTest (FT/AT), and compare the…

    ActiTest FibroTest HBV HCV

  13. The role of the non-invasive serum marker FibroTest-ActiTest in the prediction of histological stage of fibrosis and activity in children with naïve chronic hepatitis B infection.

    Sökücü S et al. · Scand J Infect Dis · 2010 Match 97

    …non-invasive serum marker FibroTest-ActiTest (FT-AT) reliably predicts the histological…

    ActiTest FibroTest HBV

  14. An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication

    Ngo Y et al. · PLoS One · 2008 Match 96

    …The use of FibroTest (FT) and ActiTest (AT), biomarkers of fibrosis and…

    ActiTest FibroTest HCV

  15. Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C.

    Poynard T et al. · Clin Chem · 2004 Match 96

    ### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…

    ActiTest FibroTest HCV

  16. Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.

    Naveau S et al. · Clin Gastroenterol Hepatol · 2005 Match 96

    …liver biopsy examination and FibroTest FibroSure (FT) results were included prospectively. Fibrosis…

    FibroTest Alcohol

  17. Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication

    Poynard T et al. · J Viral Hepat · 2009 Match 95

    The aim was to assess the utility of FibroTest-ActiTest (FT-AT…

    ActiTest FibroTest HBV

  18. Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.

    Poynard T et al. · J Hepatol · 2013 Match 95

    …of fibrosis as compared with FibroTest (FT) and liver stiffness measurement (LSM…

    FibroTest Alcohol HBV HCV +3

  19. Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.

    Poynard T et al. · Comp Hepatol · 2004 Match 95

    …In 2001, FibroTest ActiTest (FT-AT), a panel of biochemical markers, was…

    ActiTest FibroTest HCV

  20. Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.

    Poynard T et al. · PLoS One · 2008 Match 94

    …Non-invasive techniques, liver stiffness measurements (LSM) and biomarkers [FibroTest(R) (FT

    FibroTest Alcohol HBV HCV +3

  21. Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.

    El-Shabrawi MH et al. · Eur J Gastroenterol Hepatol · 2010 Match 94

    …In this study, we aimed to prospectively validate FibroTest (FT) and ActiTest…

    ActiTest FibroTest HCV

  22. Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.

    Canbakan M et al. · Nephron Clin Pract · 2011 Match 94

    …Our purpose was to compare the accuracy of the FibroTest (FT) and…

    FibroTest HCV

  23. Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.

    Alric L et al. · Transpl Int · 2009 Match 93

    To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…

    FibroTest HBV HCV

  24. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.

    Castéra L et al. · Gastroenterology · 2005 Match 93

    …The areas under the receiver operating characteristic (ROC) curve of FibroScan, FibroTest

    FibroTest HCV

  25. Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.

    Kim BK et al. · PLoS One · 2012 Match 93

    ### Background And Aims Liver stiffness measurement (LSM) and FibroTest (FT) are frequently…

    FibroTest HBV

  26. Assessment of liver fibrosis: noninvasive means.

    Poynard T et al. · Saudi J Gastroenterol · 2008 Match 92

    …Two alternatives to liver biopsy were the most evaluated FibroTest and Fibroscan…

    FibroTest Alcohol HBV HCV +3

  27. Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.

    Sène D et al. · Clin Biochem · 2006 Match 92

    …invasive biological scoring indexes (Fibrotest-Actitest [FT-AT], Forns, APRI, age-platelet…

    ActiTest FibroTest HCV

  28. Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication

    Ratziu V et al. · BMC Gastroenterol · 2006 Match 92

    …hepatitis and alcoholic liver disease (FibroTest, FT), in patients with NAFLD. ### Methods…

    FibroTest Metabolic

  29. Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.

    Poynard T et al. · Hepatology · 2003 Match 91

    Liver fibrosis and activity indexes were validated in patients infected by hepatitis…

    ActiTest FibroTest HCV

  30. Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.

    Jacqueminet S et al. · Clin Gastroenterol Hepatol · 2008 Match 91

    …with a noninvasive fibrosis biomarker (FibroTest) in patients with diabetes. ### Methods We…

    FibroTest SteatoTest Metabolic

  31. Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.

    Anastasiou J et al. · Eur J Gastroenterol Hepatol · 2010 Match 91

    …in comparison with the Fibrotest/Actitest (FT/AT), using the liver biopsy…

    ActiTest FibroTest Alcohol HBV +3

  32. Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.

    Castéra L et al. · J Hepatol · 2010 Match 90

    Fibrotest (FT) (Castera) or AST-to-Platelet Ratio Index (APRI) and FT

    FibroTest HCV

  33. FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis.

    Salkic NN et al. · Am J Gastroenterol · 2014 Match 90

    …Noninvasive alternatives such as FibroTest/Fibrosure (FT) have been developed in order…

    FibroTest HBV

  34. Meta-analyses of FibroTest diagnostic value in chronic liver disease.

    Poynard T et al. · BMC Gastroenterol · 2007 Match 90

    ### Background FibroTest (FT) is a biomarker of liver fibrosis initially validated in…

    FibroTest Alcohol HBV HCV +1

  35. Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.

    Poynard T et al. · J Hepatol · 2013 Match 89

    …Using biopsy as reference, FibroTest™ has been validated as a biomarker of…

    FibroTest HCV

  36. Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.

    Halfon P et al. · J Hepatol · 2007 Match 89

    Fibrotest (FT), APRI, FibroMeter (FM), and Hepascore (HS). ### Results Metavir stages were…

    FibroTest HCV

  37. Biomarkers of liver fibrosis.

    Poynard T et al. · Adv Clin Chem · 2008 Match 89

    FibroTest (FT) was the most studied test with 33 different populations including…

    ActiTest FibroTest SteatoTest Alcohol +5

  38. Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age.

    Poynard T et al. · BMC Gastroenterol · 2011 Match 88

    ### Background FibroTest (FT) is a validated biomarker of fibrosis. To assess the…

    ActiTest FibroTest Alcohol HBV +4

  39. Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).

    Poynard T et al. · BMC Gastroenterol · 2010 Match 88

    ### Background FibroTest and elastography have been validated as biomarkers of liver fibrosis…

    FibroTest Alcohol HBV HCV +3

  40. Noninvasive biomarkers FibroTest and ActiTest versus liver biopsy in chronic hepatitis C patients: the Middle East experience.

    Yakoob R et al. · Ann Gastroenterol · 2015 Match 88

    ### Background The aim of this study was to compare noninvasive biomarkers, FibroTest

    ActiTest FibroTest HCV

  41. Fibrotest-Actitest: the biochemical marker of liver fibrosis--the Israeli experience.

    Morali G et al. · Isr Med Assoc J · 2007 Match 88

    ### Background The Fibrotest-Actitest is a six-parameter scoring system that allows…

    ActiTest FibroTest Alcohol HBV +1

  42. Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.

    Poynard T et al. · BMJ Open · 2015 Match 87

    …The global database of the FibroTest-ActiTest, including 1,085,657 subjects…

    ActiTest FibroTest Alcohol HBV +3

  43. Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.

    Mbaye PS et al. · PLoS One · 2011 Match 87

    …For patients with LSM values below 7 kPa, FibroTest® (FT), and Fibrometer…

    FibroTest HBV

  44. FibroMAX: towards a new universal biomarker of liver disease?

    Morra R et al. · Expert Rev Mol Diagn · 2007 Match 87

    …risk of chronic liver diseases: FibroTest (BioPredictive) for the quantitative assessment of…

    ActiTest AshTest FibroTest NashTest +7

  45. FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?

    Poynard T et al. · Expert Rev Mol Diagn · 2005 Match 86

    …These include FibroTest (BioPredictive) for the quantitative assessment of fibrosis, and ActiTest…

    ActiTest FibroTest Alcohol HBV +2

  46. LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis.

    Poynard T et al. · Aliment Pharmacol Ther · 2019 Match 86

    ### Background No blood test has been shown to be effective in the…

    FibroTest LCR1 LCR2 Alcohol +3

  47. Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.

    Castera L et al. · HIV Med · 2014 Match 86

    …We compared the performances of transient elastography (TE), Fibrotest (FT), the aspartate…

    FibroTest HCV HIV

  48. Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.

    Istaces N et al. · Clin Biochem · 2015 Match 85

    ### Objectives Personalized ranges of liver fibrosis serum biomarkers such as FibroTest or…

    FibroTest HBV HCV

  49. The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.

    Imbert-Bismut F et al. · Eur J Gastroenterol Hepatol · 2009 Match 85

    …An algorithm combining the percentage of CDT, FibroTest and SteatoTest permitted to…

    FibroTest SteatoTest Alcohol

  50. Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data.

    Poynard T et al. · PLoS One · 2012 Match 85

    …non-invasive markers of fibrosis (FibroTest), steatosis (SteatoTest) and steato-hepatitis (NashTest…

    ActiTest FibroTest NashTest SteatoTest +1

  51. Effective use of FibroTest to generate decision trees in hepatitis C.

    Lau-Corona D et al. · World J Gastroenterol · 2009 Match 84

    ### Aim To assess the usefulness of FibroTest to forecast scores by constructing…

    FibroTest HCV

  52. Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies.

    Bourliere M et al. · J Viral Hepat · 2006 Match 84

    FibroTest (FT), aspartate aminotransferase to platelet ratio index (APRI) and Forns score…

    FibroTest HCV

  53. Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B.

    Houot M et al. · Aliment Pharmacol Ther · 2016 Match 84

    …0.06(0.02-0.09)], FibroTest vs. APRI [0.05 (0…

    FibroTest HBV HCV

  54. Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.

    Vermehren J et al. · BMC Gastroenterol · 2012 Match 83

    …elastography (TE) and serum biomarkers (Fibrotest [FT]). ### Methods In 202 consecutive HIV…

    FibroTest HCV HIV

  55. Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?

    Thabut D et al. · Am J Gastroenterol · 2006 Match 83

    …usefulness of biochemical markers (Fibrotest-Fibrosure/ActiTest [FT-AT]) in aged patients…

    FibroTest HCV

  56. Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.

    Castéra L et al. · Aliment Pharmacol Ther · 2011 Match 83

    …6.8 kPa, P < 0.0001), Fibrotest (0.16 vs. 0.35…

    FibroTest HBV

  57. FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate.

    Poynard T et al. · Clin Res Hepatol Gastroenterol · 2011 Match 82

    ### Background Two widely used biomarkers of fibrosis, FibroTest and liver stiffness measurement…

    FibroTest HCV

  58. Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.

    Lassailly G et al. · Eur J Gastroenterol Hepatol · 2011 Match 82

    …of noninvasive markers of fibrosis (FibroTest), steatosis (SteatoTest), and steatohepatitis (NashTest, ActiTest…

    FibroTest NashTest SteatoTest Metabolic

  59. A prospective assessment of an 'a la carte' regimen of PEG-interferon alpha2b and ribavirin combination in patients with chronic hepatitis C using biochemical markers.

    d'Arondel C et al. · J Viral Hepat · 2006 Match 82

    …had two or more RF. FibroTest and ActiTest assessed the impact of…

    ActiTest FibroTest HCV

  60. Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.

    Sadler MD et al. · Can J Gastroenterol Hepatol · 2015 Match 81

    …platelet ratio index (APRI) and FibroTest (FT) scores were also calculated. The…

    FibroTest Other

  61. Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.

    Castéra L et al. · J Hepatol · 2009 Match 81

    …index (PI), platelet count (PC), FibroTest (FT) and Lok index). ### Methods All…

    FibroTest HCV

  62. Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.

    Cacoub P et al. · J Hepatol · 2008 Match 81

    Fibrotest (FT), Hepascore (HS), Fibrometer (FM), SHASTA, APRI, Forns index, and Fib…

    FibroTest HCV HIV

  63. Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.

    Stasi C et al. · World J Gastroenterol · 2016 Match 80

    …than other, more expensive non-invasive tests, such as elastography or FibroTest.

    FibroTest HCV

  64. Applicability and variability of liver stiffness measurements according to probe position.

    Ingiliz P et al. · World J Gastroenterol · 2009 Match 80

    …The discordance rate between the reference position result and FibroTest was higher…

    FibroTest Alcohol HBV HCV +3

  65. FibroTest (FT) has similar accuracy for cirrhosis in 'intention-to-diagnose' which is superior to transient elastography (TE) in chronic hepatitis B.

    Munteanu M et al. · Liver Int · 2014 Match 80

    FibroTest HBV

  66. Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.

    Bonnard P et al. · Am J Trop Med Hyg · 2010 Match 79

    …ratio index (APRI), Fib-4, Fibrotest, Fibrometre, and Fibroscan. Elastometric thresholds were…

    FibroTest HBV

  67. [Diagnostic value of FibroTest for liver fibrosis in patients with chronic hepatitis B].

    Wang C et al. · Zhonghua Gan Zang Bing Za Zhi · 2015 Match 79

    ### Objective To determine the diagnostic value of FibroTest (FT) for liver fibrosis…

    FibroTest HBV

  68. [FibroTest-ActiTest for predicting liver fibrosis and inflammatory activity in Chinese patients with chronic hepatitis B]. Key publication

    Gui HL et al. · Zhonghua Gan Zang Bing Za Zhi · 2008 Match 79

    ### Objective To confirm the diagnostic value of FibroTest-ActiTest (FT-AT) in…

    FibroTest HBV

  69. Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.

    Kucharska M et al. · Pol Arch Intern Med · 2017 Match 78

    …Liver fibrosis was measured with shear wave elastography and FibroTest. The risk…

    FibroTest HCV

  70. Variability of the area under the receiver operating characteristic curves in the diagnostic evaluation of liver fibrosis markers: impact of biopsy length and fragmentation.

    Poynard T et al. · Aliment Pharmacol Ther · 2007 Match 78

    …The FibroTest area under the ROC curves for the diagnosis of advanced…

    FibroTest HCV

  71. Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.

    Leroy V et al. · J Hepatol · 2014 Match 78

    …describe the diagnostic performance of FibroTest®, FibroMeter®, and HepaScore® for liver fibrosis…

    FibroTest HBV HCV

  72. Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.

    Rubio A et al. · J Pediatr Gastroenterol Nutr · 2009 Match 77

    …Liver function was assessed with standard serum biochemical markers, FibroTest, ActiTest, SteatoTest…

    FibroTest HIV

  73. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

    Poynard T et al. · Diagnostics (Basel) · 2025 Match 77

    …We applied 3M to FibroTest-T2D to demonstrate this reduction of uncertainty…

    FibroTest-T2D Metabolic

  74. Biopsy as well as FibroTest/Fibrosure is suboptimal for discriminating intermediate fibrosis stages in patients with chronic hepatitis B.

    Munteanu M et al. · Am J Gastroenterol · 2014 Match 77

    FibroTest HBV

  75. Evaluation of FibroTest inter-laboratory variations requires standardization on analytical systems and should not be mixed with underpowered histological validation.

    Munteanu M et al. · Clin Chim Acta · 2010 Match 76

    FibroTest HCV

  76. Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.

    Fernandez M et al. · Eur J Gastroenterol Hepatol · 2015 Match 76

    …FS, Fibrotest, FIB-4, aspartate aminotransferase to platelet ratio index (APRI), and…

    FibroTest Alcohol

  77. Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.

    Poynard T et al. · Am J Gastroenterol · 2005 Match 76

    ### Objectives The noninvasive serum markers, FibroTest-ActiTest (FT-AT), are an alternative…

    ActiTest FibroTest HBV

  78. Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages. Key publication

    Poynard T et al. · Clin Chem · 2007 Match 75

    …standardization. ### Methods The AUCs of FibroTest (FT) for the diagnosis of advanced…

    FibroTest HCV

  79. Analytical variability of the Fibrotest proteins.

    Rosenthal-Allieri MA et al. · Clin Biochem · 2005 Match 75

    ### Objectives The analytical variability of the Fibrotest (FT) parameters raises the issue…

    FibroTest HCV

  80. Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.

    Miailhes P et al. · J Viral Hepat · 2011 Match 75

    …A sequential algorithm combining TE with biochemical score (Fibrotest) is proposed. Fifty…

    FibroTest HBV HIV

  81. Noninvasive diagnosis in alcohol-related liver disease. Review

    Hadefi A et al. · Health Sci Rep · 2020 Match 75

    …the Enhanced Liver Fibrosis test, FibroTest, and Transient Elastography are the most…

    FibroTest Alcohol

  82. FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.

    Poynard T et al. · J Hepatol · 2011 Match 74

    …The aim of the present study was to assess FibroTest (FT), a…

    FibroTest HCV

  83. Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).

    Munteanu M et al. · Comp Hepatol · 2004 Match 74

    …total bilirubin (all part of FibroTest) plus alanine aminotransferase (all part of…

    ActiTest FibroTest Alcohol HBV +3

  84. Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.

    Bonnard P et al. · J Viral Hepat · 2015 Match 74

    …serum markers (APRI, Fib4 and Fibrotest(©)). Patients had to have a LB…

    FibroTest HCV

  85. Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.

    Friedrich-Rust M et al. · BMC Gastroenterol · 2010 Match 73

    ### Background FibroTest (FT) is the most frequently used serum fibrosis marker and…

    FibroTest HBV HCV Other

  86. Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).

    Poynard T et al. · J Hepatol · 2014 Match 73

    ### Background & Aims FibroTest™ (FT) and Transient Elastography (TE) have been validated as…

    FibroTest HCV

  87. Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.

    Poynard T et al. · J Hepatol · 2012 Match 73

    …Non-invasive biomarkers such as FibroTest (FT) should allow the estimation of…

    FibroTest Alcohol HBV HCV +1

  88. Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C.

    Boursier J et al. · BMC Gastroenterol · 2011 Match 72

    …reference histological result) rates were: Fibrotest: 17.2%, FibroMeter2G: 5.6%, local…

    FibroTest HCV

  89. Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.

    Elalfy MS et al. · Ann Hepatol · 2013 Match 72

    …and transient elastography (TE) (FibroScan). FibroTest and liver biopsy were done to…

    ActiTest FibroTest HCV

  90. An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.

    Patel K et al. · J Viral Hepat · 2009 Match 72

    Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to…

    FibroTest HCV

  91. Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients.

    Sebagh M et al. · J Hepatol · 2012 Match 71

    …and 18%, respectively; in VCH, Fibrotest and transient elastography displayed poor discriminative…

    ActiTest FibroTest Alcohol HBV +4

  92. Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.

    Dai CY et al. · J Hepatol · 2010 Match 71

    …Serum HCV RNA and non-invasive markers of fibrosis (FibroTest) were tested…

    FibroTest HBV HCV

  93. Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.

    Bottero J et al. · J Hepatol · 2009 Match 71

    …The AUROCs of the Fibrotest, Hepascore, Fibrometer, and Zeng's scores ranged…

    FibroTest HBV HIV

  94. Combination of fibrosis tests: sequential or synchronous?

    Boursier J et al. · Hepatology · 2009 Match 70

    FibroTest HCV

  95. Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.

    Ratziu V et al. · Aliment Pharmacol Ther · 2007 Match 70

    …use the non-invasive biomarkers, FibroTest (FT), SteatoTest and NashTest, and to…

    FibroTest NashTest SteatoTest Metabolic

  96. ActiTest accuracy for the assessment of histological activity grades in patients with chronic hepatitis C, an overview using Obuchowski measure.

    Poynard T et al. · Gastroenterol Clin Biol · 2010 Match 70

    ### Background ActiTest (AT) is a biomarker of liver necro-inflammatory histological activity…

    ActiTest HCV

  97. Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.

    Calin R et al. · J Clin Virol · 2013 Match 69

    …by a non invasive biomarker (Fibrotest), was evaluated first, by a cross…

    FibroTest HBV HIV

  98. Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.

    Minville C et al. · Chest · 2014 Match 69

    …blood tests (SteatoTest, NashTest, and FibroTest) were used to evaluate steatosis, nonalcoholic…

    FibroTest NashTest SteatoTest Metabolic

  99. Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.

    Halfon P et al. · Antivir Ther · 2009 Match 69

    …of treatment (week 72; W72). Fibrotest, the Forn's index, age-platelet…

    FibroTest HCV HIV

  100. Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.

    Leroy V et al. · J Hepatol · 2007 Match 68

    …Using logistic regression, statistical independence was demonstrated for MP3, Fibrotest and APRI…

    FibroTest HCV

  101. [Alpha 2 macroglobulin immunoturbidimetric assays (DakoCytomation reagents) on Roche Diagnostic analysers (Modular P, Cobas Integra). Application to FibroTest-Actic-Test].

    Piton A et al. · Ann Biol Clin (Paris) · 2005 Match 68

    …it was introduced into FibroTest-ActiTest-Fibro (FT-AT-Fibro) algorithm. More…

    ActiTest FibroTest

  102. Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.

    Poynard T et al. · Aliment Pharmacol Ther · 2023 Match 68

    FibroTest-T2D NashTest-T2D SteatoTest-T2D Metabolic

  103. Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review

    Moreno C et al. · J Hepatol · 2019 Match 67

    …The commercially available Enhanced Liver Fibrosis test and FibroTest have comparable performance…

    FibroTest Alcohol

  104. [Biomarkers for liver fibrosis: advances, advantages and disadvantages].

    Cequera A et al. · Rev Gastroenterol Mex · 2014 Match 67

    Liver cirrhosis in Mexico is one of the most important causes of…

    FibroTest HCV

  105. Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication

    Poynard T et al. · BMC Gastroenterol · 2006 Match 67

    ### Background Liver biopsy is considered the gold standard for assessing histologic lesions…

    NashTest Metabolic

  106. Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.

    Morra R et al. · Aliment Pharmacol Ther · 2007 Match 66

    ### Background FibroTest has been validated for the diagnosis of liver fibrosis in…

    FibroTest Alcohol HBV HCV +1

  107. The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication

    Poynard T et al. · Comp Hepatol · 2005 Match 66

    …SteatoTest was constructed using a combination of the 6 components of FibroTest

    SteatoTest Alcohol HBV HCV +1

  108. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.

    Boursier J et al. · Clin Gastroenterol Hepatol · 2023 Match 66

    …For Fibrotest, FibroMeter, and FibroMeter^VCTE^, the decrease in specificity was related…

    FibroTest Metabolic

  109. Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.

    Traoré F et al. · BMC Infect Dis · 2015 Match 65

    …Fibrosis and hepatitis activity were measured using the Fibrotest-Actitest. A mutation…

    ActiTest FibroTest HBV

  110. Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.

    Viglino D et al. · Sci Rep · 2018 Match 65

    Chronic Obstructive Pulmonary Disease (COPD) and Non-Alcoholic Fatty Liver Disease (NAFLD…

    FibroTest NashTest SteatoTest Metabolic

  111. Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.

    Bouayad A et al. · Pan Afr Med J · 2021 Match 65

    …a non-invasive blood test (FibroTest and ActiTest) was studied in 699…

    ActiTest FibroTest HCV

  112. Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.

    Köksal İ et al. · Turk J Gastroenterol · 2018 Match 64

    …FIB-4 0.732 AUC and FibroTest 0.715 AUC indicated advanced…

    FibroTest HCV

  113. Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.

    de Lédinghen V et al. · Dig Liver Dis · 2012 Match 64

    …Severe fibrosis was predicted when FibroTest was >0.59 or liver stiffness…

    FibroTest Metabolic

  114. Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication

    Nguyen-Khac E et al. · Aliment Pharmacol Ther · 2008 Match 64

    …Fibroscan, Fibrotest, Fibrometer, Hepascore, APRI, PGA, PGAA and hyaluronic acid tests were…

    FibroTest Alcohol

  115. Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.

    Friedrich-Rust M et al. · Ultraschall Med · 2009 Match 63

    …fibrosis markers such as the FibroTest (FT) are established methods for the…

    FibroTest Alcohol HBV HCV +2

  116. The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.

    Grigorescu M et al. · J Gastrointestin Liver Dis · 2007 Match 63

    ### Aim To assess the diagnostic value of FibroTest to discriminate between insignificant…

    FibroTest HCV

  117. Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.

    Friedrich-Rust M et al. · J Cyst Fibros · 2013 Match 63

    …lobe, ARFI-left-liver-lobe, Fibrotest, Fibrotest-corrected-by-haptoglobin was 17…

    FibroTest Other

  118. Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.

    Coco B et al. · J Viral Hepat · 2007 Match 63

    …markers of fibrosis (APRI, FORNS, FibroTest and hyaluronic acid). The dynamic profiles…

    FibroTest Alcohol HBV HCV +1

  119. A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication

    Ngo Y et al. · Clin Chem · 2006 Match 62

    ### Background FibroTest, a noninvasive method of measuring biomarkers of liver fibrosis, is…

    FibroTest HCV

  120. FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy.

    Shaheen AA et al. · Am J Gastroenterol · 2007 Match 62

    …Due to the limitations of biopsy, noninvasive alternatives including FibroTest and FibroScan…

    FibroTest Alcohol HBV HCV

  121. Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.

    Crisan D et al. · Hepat Mon · 2012 Match 62

    …The association that included Fibrotest was also reliable for the improvement of…

    FibroTest HCV

  122. Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.

    Ciećko-Michalska I et al. · Arch Med Sci Atheroscler Dis · 2018 Match 61

    …SteatoTest, ActiTest and FibroTest. We compared the prevalence of metabolic disorders and…

    ActiTest FibroTest SteatoTest Metabolic

  123. Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.

    Poynard T et al. · Clin Res Hepatol Gastroenterol · 2012 Match 61

    ### Background FibroTest(®) (FT), and liver stiffness measurement (LSM) are the most validated…

    Elasto-FibroTest FibroTest HCV

  124. Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.

    Stibbe KJ et al. · Scand J Gastroenterol · 2011 Match 61

    …GBT, HA, APRI, FibroTest, Fib-4, and TE detected F01 from F234…

    FibroTest HBV HCV

  125. Real-Time Shear Wave versus Transient Elastography for Predicting Fibrosis: Applicability, and Impact of Inflammation and Steatosis. A Non-Invasive Comparison.

    Poynard T et al. · PLoS One · 2016 Match 60

    …unmet needs. ### Methods We took FibroTest as the fibrosis reference and ActiTest…

    ActiTest FibroTest SteatoTest Alcohol +3

  126. Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.

    Perazzo H et al. · Aliment Pharmacol Ther · 2014 Match 60

    …In type-2 diabetes, FibroTest predicted cardiovascular events and improved the Framingham…

    FibroTest SteatoTest Metabolic

  127. Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.

    Kucharska M et al. · Adv Clin Exp Med · 2015 Match 60

    …relevant blood parameters (e.g. FibroTest, Fibrometer, APRI index). Ease of implementation…

    FibroTest HCV

  128. Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.

    Adams LA et al. · J Gastroenterol Hepatol · 2011 Match 59

    …APRI, BARD) and complex (Hepascore, Fibrotest, FIB4) fibrosis models were calculated in…

    FibroTest Metabolic

  129. Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection.

    Parikh P et al. · Ann Transl Med · 2017 Match 59

    Chronic hepatitis B virus (HBV) infection is a major cause of liver…

    FibroTest HBV

  130. Clinical applicability of non-invasive markers for liver fibrosis in chronic hepatitis C (Letter)

    Match 59

    FibroTest HCV

  131. Optimal correlation between different instruments for Fibrotest-Actitest protein measurement in patients with chronic hepatitis C.

    Rosenthal-Allieri MA et al. · Gastroenterol Clin Biol · 2007 Match 58

    …We evaluated Fibrotest-Actitest results obtained with the two nephelemeters. ### Results Optimal…

    ActiTest FibroTest HCV

  132. Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.

    Naveau S et al. · Eur J Gastroenterol Hepatol · 2014 Match 58

    …The Fibrotest score was computed using the Biopredictive website. The overall diagnostic…

    FibroTest Alcohol

  133. Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.

    Poynard T et al. · J Hepatol · 2012 Match 58

    …Two widely used techniques, FibroTest®, and liver stiffness measurement (LSM) using Fibroscan…

    FibroTest HCV

  134. Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.

    Pais R et al. · Eur J Intern Med · 2015 Match 57

    …surrogate for IR) and fibrosis (FibroTest>0.48 as a surrogate for…

    FibroTest SteatoTest HBV HCV +1

  135. Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.

    Munteanu M et al. · Aliment Pharmacol Ther · 2016 Match 57

    …0.878 (0.864-0.892) for FibroTest and fibrosis stages, 0…

    ActiTest FibroTest SteatoTest Metabolic

  136. Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication

    Poynard T et al. · Gastroenterol Clin Biol · 2008 Match 57

    This review summarizes the methodological aspects of the interpretation of non-invasive…

    ActiTest FibroTest SteatoTest Alcohol +5

  137. Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication

    Munteanu M et al. · J Gastrointestin Liver Dis · 2008 Match 56

    ActiTest AshTest FibroTest NashTest +6

  138. [SWE elastography in assessment of liver fibrosis].

    Zaleska-Dorobisz U et al. · Postepy Hig Med Dosw (Online) · 2015 Match 56

    …using biochemical parameters (Fibrotest) or elastography. Elastography is a new diagnostic tool…

    FibroTest HBV HCV

  139. Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.

    Said Y et al. · Tunis Med · 2010 Match 56

    ### Aim To assess the diagnostic value of Fibrotest in comparison with liver…

    FibroTest HCV

  140. Glycogenic hepatopathy.

    Khoury J et al. · Hepatobiliary Pancreat Dis Int · 2018 Match 55

    …There is no role for noninvasive tests like fibroscan or fibrotest for…

    FibroTest Metabolic

  141. Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study.

    Thabut D et al. · Liver Int · 2006 Match 55

    …assess the predictive value of FibroTest, a non-invasive marker of liver…

    FibroTest Alcohol HBV HCV

  142. Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.

    Friedrich-Rust M et al. · J Clin Gastroenterol · 2010 Match 55

    …No correlation of histologic-stage was observed for FibroTest and AST to…

    FibroTest SteatoTest Other

  143. Impact of steatosis and inflammation definitions on the performance of NASH tests.

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2018 Match 54

    ### Background And Aim One of the unmet needs in subjects with metabolic…

    ActiTest FibroTest NashTest NashTest-2 +3

  144. Relationship between the Fibrotest and portal hypertension in patients with liver disease.

    Thabut D et al. · Aliment Pharmacol Ther · 2007 Match 54

    …The same day, blood samples for Fibrotest were performed. ### Results A total…

    FibroTest Alcohol HBV HCV +2

  145. The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.

    Thabut D et al. · J Hepatol · 2006 Match 54

    …AshTest was constructed using a combination of the six components of FibroTest

    AshTest Alcohol

  146. [Prognosis assessment of alcoholic liver disease: how and why?].

    Trabut JB et al. · Presse Med · 2014 Match 53

    …as biomarker tests (e.g. FibroTest(®) or FibroMetre A(®)) or hepatic elastography…

    FibroTest Alcohol

  147. Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.

    Matta B et al. · Curr HIV/AIDS Rep · 2016 Match 53

    …markers) such as APRI, FIB4, FibroTest, FibroSpect II, HepaScore, or imaging-based…

    FibroTest HBV HCV HIV

  148. Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference.

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2018 Match 53

    …A combination of NIT-NASHs with FibroTest (AUROC=0.800; 0.759…

    FibroTest NashTest SteatoTest Metabolic

  149. Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.

    Beckebaum S et al. · Transplantation · 2010 Match 52

    …0.79 and 0.70 (FibroTest), 0.78 and 0.71 (FIB…

    FibroTest Alcohol HBV HCV +2

  150. Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.

    Gangadharan B et al. · PLoS One · 2012 Match 52

    …to the markers used in FibroTest, Enhanced Liver Fibrosis (ELF) test, Hepascore…

    FibroTest HCV

  151. External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B.

    Poynard T et al. · Gastro Hep Adv · 2022 Match 52

    ### Background And Aims The liver cancer risk test (LCR1-LCR2) is a…

    FibroTest LCR1 LCR2 Surveillance-FibroTest +1

  152. Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.

    Poynard T et al. · Antivir Ther · 2010 Match 51

    …In a comparison of HCV patients with controls, the FibroTest pFPy was…

    ActiTest FibroTest HBV HCV +1

  153. Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.

    Chou R et al. · Ann Intern Med · 2013 Match 51

    …platelet ratio index (APRI), FibroIndex, FibroTest, and Forns index had median positive…

    FibroTest HCV

  154. Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.

    Stevenson M et al. · Health Technol Assess · 2012 Match 51

    …Three studies of FibroTest, no relevant studies of FibroMax, and six studies…

    FibroTest Alcohol

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