Scientific publications for BioPredictive non-invasive diagnostics

Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.

133/433 Matches for
“AUROC, area under the receiver operating curve”

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  1. Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.

    Lassailly G et al. · Eur J Gastroenterol Hepatol · 2011 Match 100

    The area under the receiver operating characteristic curves (AUROC), sensitivity, specificity, positive…

    FibroTest NashTest SteatoTest Metabolic

  2. SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.

    Sebastiani G et al. · Hepatology · 2009 Match 100

    …1% accuracy (area under the receiver operating characteristic curve = 0.89; 95…

    FibroTest HCV

  3. Variability of the area under the receiver operating characteristic curves in the diagnostic evaluation of liver fibrosis markers: impact of biopsy length and fragmentation.

    Poynard T et al. · Aliment Pharmacol Ther · 2007 Match 100

    ### Background The area under the receiver operating characteristic (ROC) curve is widely…

    FibroTest HCV

  4. Prognostic value of liver fibrosis biomarkers: a meta-analysis.

    Poynard T et al. · Gastroenterol Hepatol (N Y) · 2011 Match 99

    …liver-related death, the areas under the receiver operating characteristic curves (AUROCs…

    FibroTest Alcohol HBV HCV +3

  5. Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.

    Trnačević E et al. · Med Glas (Zenica) · 2021 Match 99

    …According to areas under the Receiver Operating Characteristics (AUROC), the best performing…

    FibroTest HCV

  6. The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.

    Imbert-Bismut F et al. · Eur J Gastroenterol Hepatol · 2009 Match 99

    …with EAD, the area under the receiver operating characteristic curve =0.89…

    FibroTest SteatoTest Alcohol

  7. Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study.

    Thabut D et al. · Liver Int · 2006 Match 98

    …Sensitivity, specificity, predictive values and area under the receiver operating characteristic curves…

    FibroTest Alcohol HBV HCV

  8. Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.

    Anastasiou J et al. · Eur J Gastroenterol Hepatol · 2010 Match 98

    The areas under the receiver operating characteristic curve of FS and FT…

    ActiTest FibroTest Alcohol HBV +3

  9. Relationship between the Fibrotest and portal hypertension in patients with liver disease.

    Thabut D et al. · Aliment Pharmacol Ther · 2007 Match 97

    The areas under the receiver operating characteristic curves for the diagnosis of…

    FibroTest Alcohol HBV HCV +2

  10. Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.

    Fernandez M et al. · Eur J Gastroenterol Hepatol · 2015 Match 97

    ### Objective Fibroscan (FS) is a reliable noninvasive method for the diagnosis of…

    FibroTest Alcohol

  11. FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.

    Zeremski M et al. · BMC Gastroenterol · 2014 Match 97

    …mild fibrosis (area under receiver operating characteristic [AUROC] curve = 0.77; 95…

    ActiTest FibroTest HBV

  12. Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.

    Kim BK et al. · PLoS One · 2012 Match 96

    …cirrhosis (F = 4), areas under receiver operating characteristic curves (AUROCs) of FT…

    FibroTest HBV

  13. Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes.

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2020 Match 96

    area under the receiver operating curve (AUROC) for F3F4 diagnosis from the

    FibroTest NashTest-2 SteatoTest-2 Metabolic

  14. Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.

    Naveau S et al. · Eur J Gastroenterol Hepatol · 2014 Match 96

    …of the area under the receiver operating characteristic (AUROC) curve. The Obuchowski…

    FibroTest Alcohol

  15. Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.

    de Lédinghen V et al. · Liver Int · 2012 Match 95

    …score, Area Under the Receiver-Operating Characteristics (ROC) curves (AUROC)s were…

    SteatoTest Metabolic

  16. FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.

    Patel K et al. · World J Gastroenterol · 2011 Match 95

    …61, respectively, with area under the receiver-operating curve of 0.82…

    FibroTest HCV

  17. Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.

    Vergniol J et al. · Gastroenterology · 2011 Match 94

    …We evaluated the abilities of liver stiffness, results from noninvasive tests for…

    FibroTest HCV HIV

  18. Noninvasive assessment of portal hypertension in patients with cirrhosis.

    Thabut D et al. · Hepatology · 2011 Match 94

    …still under investigation. The assessment of severe portal hypertension by the presence…

    FibroTest Alcohol HBV HCV +3

  19. Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.

    Poynard T et al. · Hepatol Commun · 2023 Match 94

    The stratified TB was classified as GS when TB >90th centile; <10th…

    FibroTest

  20. Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.

    Said Y et al. · Tunis Med · 2010 Match 93

    Receiver operating characteristics (ROC) curves , the sensitivity, specificity, positive and negative predictive…

    FibroTest HCV

  21. The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.

    Boursier J et al. · Liver Int · 2009 Match 93

    …significantly higher area under the receiver operating characteristic curve (0.892) than…

    FibroTest Alcohol HBV HCV +2

  22. Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.

    Poynard T et al. · Curr Hepat Rep · 2011 Match 93

    …advanced fibrosis, the standardized area under the receiver operating curve was 0…

    FibroTest HBV

  23. Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.

    Kim BK et al. · PLoS One · 2012 Match 92

    …fibrosis stages. ### Results Areas under receiver operating characteristic curves (AUROCs) to predict…

    FibroTest HBV

  24. Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.

    Voican CS et al. · Liver Int · 2017 Match 92

    …evaluated by the area under the receiver operating characteristic (AUROC) curves and…

    FibroTest Alcohol

  25. Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.

    Miailhes P et al. · J Viral Hepat · 2011 Match 91

    The diagnosis accuracy of TE was calculated using receiver operating characteristic (ROC…

    FibroTest HBV HIV

  26. Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.

    Friedrich-Rust M et al. · J Clin Gastroenterol · 2010 Match 91

    The adjusted accuracy (area under the receiver operating characteristic) for the diagnosis…

    FibroTest SteatoTest Other

  27. Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B.

    Myers RP et al. · J Hepatol · 2003 Match 91

    …activity ((areas under receiver operating characteristic (ROC) curves (AUROC), 0.81-0…

    ActiTest FibroTest HBV

  28. Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.

    Bonnard P et al. · Am J Trop Med Hyg · 2010 Match 90

    The area under receiver operating characteristic (AUROC) curves was 0.61, 0…

    FibroTest HBV

  29. Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.

    Bonnard P et al. · J Viral Hepat · 2015 Match 90

    The area under receiver operating characteristic curves was 0.70, 0.76…

    FibroTest HCV

  30. The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2019 Match 90

    …Areas under the receiver operating characteristic curve varied in the SteatoTest-2…

    NashTest-2 SteatoTest-2 Metabolic

  31. An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.

    Patel K et al. · J Viral Hepat · 2009 Match 89

    …a good area under the receiver operating characteristic curve (0.89 and…

    FibroTest HCV

  32. Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.

    Schmid P et al. · PLoS One · 2015 Match 89

    …intervals. ### Results Area under the receiver operating characteristic curve (AUROC) for significant…

    FibroTest HCV HIV

  33. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.

    Boursier J et al. · Clin Gastroenterol Hepatol · 2023 Match 88

    …Results NIT areas under the receiver operating characteristic curve were significantly lower…

    FibroTest Metabolic

  34. Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.

    Peta V et al. · World J Hepatol · 2025 Match 88

    The areas under the ROC curve values for activity biomarkers were 0…

    ActiTest FibroTest AIH

  35. Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.

    Chou R et al. · Ann Intern Med · 2013 Match 88

    …cutoffs and areas under the receiver-operating characteristic curve (AUROCs) of 0…

    FibroTest HCV

  36. Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C.

    Boursier J et al. · Eur J Gastroenterol Hepatol · 2009 Match 87

    The corresponding area under the receiver operating characteristics were FibroMeter: 0.885…

    FibroTest HCV

  37. Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.

    Cheng J et al. · PLoS One · 2015 Match 87

    the liver histology by ROC curve analysis in CHB patients. The reproducibility…

    FibroTest HBV

  38. Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Key publication

    Nguyen-Khac E et al. · Aliment Pharmacol Ther · 2008 Match 87

    …Liver stiffness cut-offs were determined using receiver-operating characteristic (ROC) curves…

    FibroTest Alcohol

  39. Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.

    Zelber-Sagi S et al. · World J Gastroenterol · 2013 Match 86

    …yielded an area under the receiver operating characteristic curve (AUROC) of 0…

    SteatoTest Metabolic

  40. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.

    Castéra L et al. · Gastroenterology · 2005 Match 86

    The areas under the receiver operating characteristic (ROC) curve of FibroScan, FibroTest…

    FibroTest HCV

  41. Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.

    Sebastiani G et al. · J Viral Hepat · 2008 Match 85

    …accuracy and area under the receiver operating characteristic curve (AUROC). All noninvasive…

    FibroTest HCV

  42. The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.

    Mallet V et al. · Aliment Pharmacol Ther · 2009 Match 85

    …with an area under the receiving operating characteristic curve of 0.81…

    FibroTest HBV

  43. Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis.

    Brener S · Ont Health Technol Assess Ser · 2015 Match 85

    The analysis also aimed to compare the diagnostic accuracy of transient elastography…

    Elasto-FibroTest FibroTest Alcohol HBV +3

  44. Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.

    Flores-Calderón J et al. · Ann Hepatol · 2012 Match 84

    ### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…

    FibroTest

  45. Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication

    Poynard T et al. · J Viral Hepat · 2009 Match 84

    the area under the receiver operating characteristics curves (AUROCs) for the diagnosis…

    ActiTest FibroTest HBV

  46. Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.

    Crisan D et al. · Indian J Med Res · 2017 Match 84

    Area under the receiver operating characteristic curve for SVR was 0.875…

    ActiTest FibroTest SteatoTest HCV

  47. FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients.

    Vallet-Pichard A et al. · Hepatology · 2006 Match 83

    FibroTest HCV

  48. Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.

    Fierbinteanu-Braticevici C et al. · World J Gastroenterol · 2009 Match 83

    …expressed as area under receiver operating characteristic curve (AUROC) had a validity…

    FibroTest HCV

  49. Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference.

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2018 Match 82

    …with an area under the receiver operating characteristic curve (AUROC) of 0…

    FibroTest NashTest SteatoTest Metabolic

  50. Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.

    Sebastiani G et al. · Aliment Pharmacol Ther · 2012 Match 82

    …Three algorithms based on the combination of Fibrotest, Forns' index and AST…

    FibroTest HCV

  51. Noninvasive biomarkers FibroTest and ActiTest versus liver biopsy in chronic hepatitis C patients: the Middle East experience.

    Yakoob R et al. · Ann Gastroenterol · 2015 Match 82

    The observed area under the receiver operating characteristic curve (AUROC) for advanced…

    ActiTest FibroTest HCV

  52. Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.

    Beckebaum S et al. · Transplantation · 2010 Match 81

    The corresponding area under the receiver operating characteristic (AUROC) curves for F…

    FibroTest Alcohol HBV HCV +2

  53. The predictive value of Fibrotest vs. APRI for the diagnosis of fibrosis in chronic hepatitis C.

    Le Calvez S et al. · Hepatology · 2004 Match 81

    FibroTest HCV

  54. Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.

    Friedrich-Rust M et al. · Ultraschall Med · 2009 Match 81

    The diagnostic accuracy expressed as areas under ROC curves was 0.84…

    FibroTest Alcohol HBV HCV +2

  55. Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.

    Naveau S et al. · Clin Gastroenterol Hepatol · 2005 Match 80

    …F0-F1, the FT area under the ROC curves (AUROC) = .84 (.03…

    FibroTest Alcohol

  56. Optimization and robustness of blood tests for liver fibrosis and cirrhosis.

    Calès P et al. · Clin Biochem · 2010 Match 80

    ### Objectives To optimize the performance and feasibility of fibrosis blood tests and…

    FibroTest HCV

  57. Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.

    Rhodes FA et al. · J Gastroenterol Hepatol · 2021 Match 79

    Area under the receiver operating characteristic curves for outcome prediction ranged from…

    FibroTest Alcohol

  58. Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.

    Alric L et al. · Transpl Int · 2009 Match 79

    The area under the receiver-operating characteristic curve for mild fibrosis stage…

    FibroTest HBV HCV

  59. Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease.

    Thiele M et al. · Gastroenterology · 2018 Match 79

    …with an area under the receiver operating characteristic curve (AUROC) of 0…

    FibroTest Alcohol

  60. Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.

    Park MS et al. · Liver Int · 2015 Match 78

    The areas under receiver-operating characteristic curves of LS, FT, LS + FT…

    FibroTest HBV

  61. Biomarkers of liver fibrosis.

    Poynard T et al. · Adv Clin Chem · 2008 Match 78

    …assessed using standardized area under the receiver operating characteristics (ROC) curves was…

    ActiTest FibroTest SteatoTest Alcohol +5

  62. Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.

    Cassinotto C et al. · Radiology · 2013 Match 78

    the diagnosis of cirrhosis (area under under the receiver operating characteristic curve

    FibroTest Alcohol HBV HCV +2

  63. An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication

    Ngo Y et al. · PLoS One · 2008 Match 77

    …ALT when compared using area under the ROC curves [0.89 (95…

    ActiTest FibroTest HCV

  64. Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.

    Bosselut N et al. · Clin Chim Acta · 2013 Match 77

    The new score was constructed by non linear regression using the most…

    FibroTest HCV

  65. Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.

    de Lédinghen V et al. · J Pediatr Gastroenterol Nutr · 2007 Match 76

    the diagnosis of cirrhosis, the area under the receiver operating characteristic curve

    FibroTest HBV HCV Other

  66. A novel panel of blood markers to assess the degree of liver fibrosis.

    Calès P et al. · Hepatology · 2005 Match 76

    …hepatitis, the area under the receiving operator characteristic (AUROC) curve for stages…

    FibroTest Alcohol HBV HCV

  67. Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.

    Poynard T et al. · Hepatology · 2003 Match 76

    …activity, the area under the receiver operating characteristics curve of the activity…

    ActiTest FibroTest HCV

  68. Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.

    Calès P et al. · J Hepatol · 2010 Match 75

    …Within these populations, the diagnostic target, significant fibrosis (Metavir F > or = 2…

    FibroTest HCV HIV

  69. Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.

    Friedrich-Rust M et al. · BMC Gastroenterol · 2010 Match 75

    The accuracy (AUROC) for the diagnosis of significant fibrosis (F≥2) for…

    FibroTest HBV HCV Other

  70. Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.

    Poynard T et al. · PLoS One · 2008 Match 75

    The hypothesis was that the concordance between LSM and FT, would be…

    FibroTest Alcohol HBV HCV +3

  71. A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.

    Boursier J et al. · Am J Gastroenterol · 2011 Match 74

    ### Objectives Precise evaluation of the level of liver fibrosis is recommended in…

    FibroTest HCV

  72. Biopsy as well as FibroTest/Fibrosure is suboptimal for discriminating intermediate fibrosis stages in patients with chronic hepatitis B.

    Munteanu M et al. · Am J Gastroenterol · 2014 Match 74

    FibroTest HBV

  73. Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.

    Poynard T et al. · Comp Hepatol · 2004 Match 73

    …system, the areas under the receiver operating characteristics curves (AUROC) ranged from…

    ActiTest FibroTest HCV

  74. [Diagnostic value of FibroTest for liver fibrosis in patients with chronic hepatitis B].

    Wang C et al. · Zhonghua Gan Zang Bing Za Zhi · 2015 Match 73

    …Calculation of the area under the ROC curves (AUROC) was performed to…

    FibroTest HBV

  75. Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.

    López Tórrez SM et al. · Front Nutr · 2024 Match 73

    …for the summary area under the receiver operating characteristic (sAUROC) curve, according…

    FibroTest Metabolic

  76. Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.

    Poynard T et al. · Clin Gastroenterol Hepatol · 2012 Match 72

    …of the standard area under the receiver-operator characteristic curve (AUROC). ### Methods…

    FibroTest Alcohol HBV HCV +3

  77. Meta-analyses of FibroTest diagnostic value in chronic liver disease.

    Poynard T et al. · BMC Gastroenterol · 2007 Match 72

    …Methods The main end points were the FT area under the ROC…

    FibroTest Alcohol HBV HCV +1

  78. Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.

    Cacoub P et al. · J Hepatol · 2008 Match 72

    The AUROC and the rate of well-classified patients were compared to…

    FibroTest HCV HIV

  79. Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.

    Matta B et al. · Curr HIV/AIDS Rep · 2016 Match 71

    …Liver biopsy is currently considered as the gold standard for fibrosis assessment…

    FibroTest HBV HCV HIV

  80. Assessment of liver fibrosis: noninvasive means.

    Poynard T et al. · Saudi J Gastroenterol · 2008 Match 71

    the diagnosis of advanced fibrosis assessed using standardized area under the ROC…

    FibroTest Alcohol HBV HCV +3

  81. Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication

    Naveau S et al. · Hepatology · 2009 Match 70

    …Biomarkers were compared using univariate area under the ROC curves (AUROC) and…

    ActiTest AshTest FibroTest Alcohol

  82. The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.

    Thabut D et al. · J Hepatol · 2006 Match 70

    The AshTest area under the ROC curves for moderate-severe ASH was…

    AshTest Alcohol

  83. FibroTest is effective in patients with normal transaminases, when accuracy is standardized on fibrosis stage prevalence.

    Poynard T et al. · J Viral Hepat · 2008 Match 70

    FibroTest HCV

  84. Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.

    Vilar-Gomez E et al. · J Hepatol · 2018 Match 69

    The correct identification of patients at increased risk of non-alcoholic steatohepatitis…

    FibroTest Metabolic

  85. Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.

    Vermehren J et al. · Liver Int · 2012 Match 69

    The diagnostic accuracy (AUROC) for the diagnosis of large oesophageal varices was…

    FibroTest Alcohol HBV HCV +3

  86. The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy.

    Xu XY et al. · PLoS One · 2014 Match 69

    The areas under the SROC curve for APRI, FIB-4, and FibroTest…

    FibroTest HBV

  87. Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.

    El-Shabrawi MH et al. · Eur J Gastroenterol Hepatol · 2010 Match 68

    The FT area under the receiver operating characteristic curve (AUROC) is 0…

    ActiTest FibroTest HCV

  88. Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study).

    Degos F et al. · J Hepatol · 2010 Match 68

    The overall accuracy of FibroScan® was high (AUROC 0.89 and 0…

    FibroTest HBV HCV HIV

  89. FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication

    Halfon P et al. · Gastroenterol Clin Biol · 2008 Match 67

    …For diagnostic value, the main endpoint was the FT area under the

    FibroTest Alcohol HBV HCV +2

  90. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

    Poynard T et al. · Diagnostics (Basel) · 2025 Match 67

    area under the characteristic curve (wAUROC) instead of the binary AUROC, and…

    FibroTest-T2D Metabolic

  91. Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.

    Castéra L et al. · J Hepatol · 2010 Match 67

    ### Background & Aims Non-invasive assessment of liver fibrosis is a challenging area

    FibroTest HCV

  92. Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.

    Patel K et al. · Aliment Pharmacol Ther · 2016 Match 66

    …Among the 33% of patients with +/-1 Ishak stage change, FS changes…

  93. Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data.

    Poynard T et al. · PLoS One · 2012 Match 66

    The area under the ROC curves (AUROC), sensitivity, specificity, positive and negative…

    ActiTest FibroTest NashTest SteatoTest +1

  94. ActiTest accuracy for the assessment of histological activity grades in patients with chronic hepatitis C, an overview using Obuchowski measure.

    Poynard T et al. · Gastroenterol Clin Biol · 2010 Match 66

    The main end points were the area under the ROC curves (AUROCs…

    ActiTest HCV

  95. External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV.

    Poynard T et al. · JHEP Rep · 2021 Match 65

    ### Background & Aims The Liver Cancer Risk test algorithm (LCR1-LCR2) is a…

    LCR1 LCR2 HCV

  96. Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.

    Braha A et al. · J Clin Med · 2024 Match 65

    …g/L (area under the receiver operating characteristic curve (AUROC) = 0.782…

    FibroTest Metabolic

  97. The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.

    Sebastiani G et al. · Aliment Pharmacol Ther · 2011 Match 64

    …as observed area under the ROC curve (ObAUROC) and AUROC adjusted for…

    FibroTest HBV HCV HIV +1

  98. Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.

    Zarski JP et al. · J Hepatol · 2012 Match 64

    …For the 436 patients having all the blood tests, AUROC's ranged…

    FibroTest HCV

  99. Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".

    Perazzo H et al. · Clin Res Hepatol Gastroenterol · 2014 Match 64

    ### Background The aspartate aminotransferase platelet ratio index (APRI) is a validated, non…

    FibroTest Alcohol HBV HCV +1

  100. Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.

    de Lédinghen V et al. · Aliment Pharmacol Ther · 2013 Match 63

    …However, in patients chronically infected with hepatitis B virus (HBV), only the

    FibroTest HBV

  101. Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication

    Poynard T et al. · BMC Gastroenterol · 2006 Match 63

    The area under the ROC curves (AUROC), sensitivity (Se), specificity (Sp), and…

    NashTest Metabolic

  102. Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication

    Ratziu V et al. · BMC Gastroenterol · 2006 Match 63

    The area under the ROC curves (AUROC), sensitivity (Se), specificity (Sp), positive…

    FibroTest Metabolic

  103. Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.

    Poynard T et al. · Ann Intern Med · 2013 Match 62

    FibroTest HCV

  104. Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.

    Sturm N et al. · Liver Int · 2013 Match 62

    …from naïve patients, standardized for the spectrum of Metavir fibrosis stages, were…

    FibroTest HBV HCV

  105. Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication

    Poynard T et al. · Gastroenterol Clin Biol · 2008 Match 61

    This review summarizes the methodological aspects of the interpretation of non-invasive…

    ActiTest FibroTest SteatoTest Alcohol +5

  106. Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.

    Morra R et al. · Aliment Pharmacol Ther · 2007 Match 61

    The area under the receiver operating curve (AUROC) of the proteomic index…

    FibroTest Alcohol HBV HCV +1

  107. Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.

    Castera L et al. · HIV Med · 2014 Match 61

    …measuring the area under the receiver-operating characteristic curve (AUROC) and calculating…

    FibroTest HCV HIV

  108. Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.

    Poynard T et al. · J Hepatol · 2012 Match 60

    The analysis of the discordances between pairs suggested that the variability of…

    FibroTest HCV

  109. The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.

    Grigorescu M et al. · J Gastrointestin Liver Dis · 2007 Match 60

    …For FibroTest the observed area under ROC (ObAUROC) for the discrimination between…

    FibroTest HCV

  110. Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.

    Munteanu M et al. · Aliment Pharmacol Ther · 2016 Match 60

    …Contemporaneous biopsies were blindly assessed using the new steatosis, activity and fibrosis…

    ActiTest FibroTest SteatoTest Metabolic

  111. Fibrotest-Actitest: the biochemical marker of liver fibrosis--the Israeli experience.

    Morali G et al. · Isr Med Assoc J · 2007 Match 59

    The AUROC curve comparing the Fibrotest with liver biopsy with a cutoff…

    ActiTest FibroTest Alcohol HBV +1

  112. Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.

    Sadler MD et al. · Can J Gastroenterol Hepatol · 2015 Match 59

    Area under ROC curve for FS, APRI and FT for the detection…

    FibroTest Other

  113. Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review

    Moreno C et al. · J Hepatol · 2019 Match 58

    …Liver biopsy is still considered the gold standard for establishing a definite…

    FibroTest Alcohol

  114. Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.

    Denimal D et al. · Cardiovasc Diabetol · 2024 Match 58

    The primary objective of the present study was to investigate whether the

    ActiTest FibroTest NashTest SteatoTest +1

  115. FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate.

    Poynard T et al. · Clin Res Hepatol Gastroenterol · 2011 Match 58

    the standard area under the ROC curve (sAUROC) which is not the

    FibroTest HCV

  116. Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.

    Pokorska-Śpiewak M et al. · Clin Exp Hepatol · 2017 Match 57

    ### Aim Of The Study Was to evaluate liver disease severity in children…

    ActiTest FibroTest HBV HCV

  117. Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review.

    Kucharska M et al. · Adv Clin Exp Med · 2015 Match 57

    Haemophilia is an entity, wherein the HCV infection rate is greater than…

    FibroTest HCV

  118. Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.

    Mbaye PS et al. · PLoS One · 2011 Match 57

    ### Background And Aims Despite the high prevalence of chronic hepatitis B (CHB…

    FibroTest HBV

  119. Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis.

    Castera L · J Viral Hepat · 2009 Match 56

    The limitations of liver biopsy (invasive procedure, sampling errors, inter-observer variability…

    FibroTest HBV HCV HIV

  120. Noninvasive evaluation of NAFLD.

    Castera L et al. · Nat Rev Gastroenterol Hepatol · 2013 Match 56

    …Of the noninvasive serum markers, the NAFLD fibrosis score is the most…

    ActiTest FibroTest NashTest SteatoTest +1

  121. FibroMAX: towards a new universal biomarker of liver disease?

    Morra R et al. · Expert Rev Mol Diagn · 2007 Match 55

    Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the

    ActiTest AshTest FibroTest NashTest +7

  122. Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.

    Lemoine M et al. · J Acquir Immune Defic Syndr · 2019 Match 55

    …Performance was considered as good if area under a receiver operating characteristic…

    FibroTest NashTest SteatoTest HIV

  123. Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.

    Rudler M et al. · PLoS One · 2015 Match 55

    The high AshTest performance was confirmed both for the binary outcome [AUROC

    AshTest Alcohol

  124. Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.

    Poynard T et al. · Clin Res Hepatol Gastroenterol · 2012 Match 54

    area under the ROC curve (AUROC), "Obuchowski method" (OBU) and 1 TAGS…

    Elasto-FibroTest FibroTest HCV

  125. Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.

    Poynard T et al. · J Hepatol · 2013 Match 54

    The aim was to assess the applicability and performances of SWE for…

    FibroTest Alcohol HBV HCV +3

  126. Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.

    Peta V et al. · PLoS One · 2017 Match 54

    The primary objective was to analyze the performance (AUROC) of ActiTest components…

    ActiTest FibroTest Other

  127. Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.

    Calès P et al. · Gastroenterol Clin Biol · 2008 Match 53

    ### Objective To evaluate the rates of reliable diagnosis of cirrhosis by two…

    FibroTest HCV

  128. The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication

    Poynard T et al. · Comp Hepatol · 2005 Match 53

    …SteatoTest area under the ROC curves was 0.79 (SE = 0.03…

    SteatoTest Alcohol HBV HCV +1

  129. Noninvasive diagnosis in alcohol-related liver disease. Review

    Hadefi A et al. · Health Sci Rep · 2020 Match 52

    …In this review, we summarize the current status of the noninvasive assessment…

    FibroTest Alcohol

  130. Non-invasive markers for hepatic fibrosis.

    Baranova A et al. · BMC Gastroenterol · 2011 Match 52

    With great advancements in the therapeutic modalities used for the treatment of…

    FibroTest Alcohol HBV HCV +3

  131. EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication

    European Association for Study of Liver et al. · J Hepatol · 2015 Match 52

    FibroTest Alcohol HBV HCV +3

  132. Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.

    Stevenson M et al. · Health Technol Assess · 2012 Match 51

    ### Background Excessive alcohol consumption may lead to the development of alcohol-related…

    FibroTest Alcohol

  133. EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.

    European Association for the Study of the Liver (EASL) et al. · Obes Facts · 2016 Match 51

    FibroTest SteatoTest Metabolic

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