Scientific publications for BioPredictive non-invasive diagnostics

Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.

59/433 Matches for
“Type 2 Diabetes Mellitus”

“Type 2 Diabetes Mellitus” Clear all
  1. Glycogenic hepatopathy.

    Khoury J et al. · Hepatobiliary Pancreat Dis Int · 2018 Match 100

    …associated with uncontrolled diabetes mellitus, most commonly type 1, expressed as right…

    FibroTest Metabolic

  2. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.

    Boursier J et al. · Clin Gastroenterol Hepatol · 2023 Match 100

    …be less accurate in type 2 diabetes mellitus (T2DM). We aimed to…

    FibroTest Metabolic

  3. Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review

    Bril F et al. · Diabetes Care · 2017 Match 99

    …Endocrinologists and those caring for patients with type 2 diabetes mellitus (T2DM…

    FibroTest Metabolic

  4. Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.

    Bril F et al. · J Investig Med · 2019 Match 98

    …panels in patients with type 2 diabetes mellitus (T2DM). All patients underwent…

    ActiTest FibroTest NashTest SteatoTest +1

  5. PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.

    Petit JM et al. · Liver Int · 2011 Match 97

    …in unselected patients with type 2 diabetes. ### Design, Setting And Participants Two…

    FibroTest Metabolic

  6. Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes.

    Bril F et al. · Diabetes Care · 2020 Match 96

    …assessed in patients with type 2 diabetes mellitus (T2DM). ### Research Design And…

    FibroTest NashTest-2 Metabolic

  7. Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.

    Braha A et al. · J Clin Med · 2024 Match 95

    …LVDD) in patients with type 2 diabetes mellitus (T2DM). **Methods**: This single…

    FibroTest Metabolic

  8. Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.

    Petroff D et al. · Dig Liver Dis · 2018 Match 95

    FibroTest Metabolic

  9. Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.

    Guiu B et al. · Eur Radiol · 2012 Match 94

    Type-2 diabetes provides an interesting model for assessing liver steatosis. Clinico…

    SteatoTest Metabolic

  10. Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.

    Meritsi A et al. · Clin Diabetes · 2022 Match 93

    ActiTest FibroTest NashTest-2 Metabolic

  11. Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.

    Denimal D et al. · Cardiovasc Diabetol · 2024 Match 92

    …risk in individuals with type 2 diabetes (T2D). The primary objective of…

    ActiTest FibroTest NashTest SteatoTest +1

  12. Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.

    Poynard T et al. · Aliment Pharmacol Ther · 2021 Match 91

    …needs in patients with type 2 diabetes mellitus (T2DM) is the prediction…

    FibroTest NashTest-2 SteatoTest Metabolic

  13. Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study.

    Denimal D et al. · Cardiovasc Diabetol · 2025 Match 90

    …calcification in individuals with type 2 diabetes (T2D) remains unclear. This study…

    ActiTest FibroTest NashTest SteatoTest +1

  14. Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.

    de Lédinghen V et al. · Dig Liver Dis · 2012 Match 89

    …Consecutive patients with type 1 or 2 diabetes had clinical, biological parameters…

    FibroTest Metabolic

  15. European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.

    Sberna AL et al. · Diabet Med · 2018 Match 89

    Type 2 diabetes. ### Methods A total of 179 people with Type 2

    FibroTest NashTest Metabolic

  16. Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.

    Khalaf N et al. · Clin Gastroenterol Hepatol · 2015 Match 88

    …their caffeine from coffee (50.2% vs. 43.0%; P = .035). Hepatoprotective…

    FibroTest HCV

  17. Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes.

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2020 Match 87

    type-2-diabetes in comparison with patients without type-2-diabetes. These…

    FibroTest NashTest-2 SteatoTest-2 Metabolic

  18. Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.

    White DL et al. · Hepatology · 2012 Match 86

    …1.86-6.54 versus OR(adjusted advanced inflammatory activity) = 2.23…

    ActiTest FibroTest HCV

  19. External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV.

    Poynard T et al. · JHEP Rep · 2021 Match 85

    …3, alcohol consumption, and type 2 diabetes mellitus. ### Conclusions The results showed…

    LCR1 LCR2 HCV

  20. The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.

    Lynch M et al. · JAMA Dermatol · 2014 Match 84

    …if abnormalities in at least 2 tests (serial PIIINP, TE, or FibroTest…

    FibroTest Other

  21. Response to: Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications, by Jerome Boursier et al.

    Poynard T et al. · Clin Gastroenterol Hepatol · 2023 Match 84

    FibroTest Metabolic

  22. Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19.

    Deckmyn O et al. · Biomedicines · 2022 Match 83

    …or without type 2 diabetes mellitus (T2DM), alpha-2 macroglobulin (A2M), apolipoprotein…

    FibroTest Metabolic

  23. Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.

    Copaci I et al. · Rom J Intern Med · 2015 Match 82

    ### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance…

    SteatoTest Metabolic

  24. EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.

    European Association for the Study of the Liver (EASL) et al. · Obes Facts · 2016 Match 81

    FibroTest SteatoTest Metabolic

  25. Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.

    Perazzo H et al. · Aliment Pharmacol Ther · 2014 Match 80

    …In type-2 diabetes, FibroTest predicted cardiovascular events and improved the Framingham…

    FibroTest SteatoTest Metabolic

  26. Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.

    Poynard T et al. · Hepatol Commun · 2023 Match 79

    …of GS versus 3.7% (2,819/76,809) using the historical…

    FibroTest

  27. The non-invasive assessment of hepatic fibrosis.

    Gheorghe G et al. · J Formos Med Assoc · 2021 Match 78

    type methods for the evaluation of hepatic fibrosis; usually, there are 2

    ActiTest FibroTest Alcohol HBV +2

  28. Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.

    Viglino D et al. · Sci Rep · 2018 Match 78

    …mortality (Hazard ratio [95% CI]: 2.75 [1.26; 6.03]) than…

    FibroTest NashTest SteatoTest Metabolic

  29. Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication

    Munteanu M et al. · J Gastrointestin Liver Dis · 2008 Match 77

    ActiTest AshTest FibroTest NashTest +6

  30. Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.

    Ciećko-Michalska I et al. · Arch Med Sci Atheroscler Dis · 2018 Match 76

    ### Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common…

    ActiTest FibroTest SteatoTest Metabolic

  31. Finasteride and methadone use and risk of advanced hepatitis C related liver disease.

    White DL et al. · Dig Dis Sci · 2012 Match 75

    …White male methadone-users had 2.1-fold excess advanced inflammation risk…

    ActiTest FibroTest HCV

  32. Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.

    Grattagliano I et al. · Ann Hepatol · 2013 Match 74

    2% had hypertransaminasemia. The percent of patients with overweight, obesity, diabetes, hypertension…

    ActiTest FibroTest NashTest SteatoTest +1

  33. A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.

    Ratziu V et al. · J Hepatol · 2011 Match 73

    ### Background & Aims Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease associated with…

    FibroTest Metabolic

  34. The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.

    Younossi ZM et al. · Gastroenterology · 2021 Match 73

    …52.5% with F4 NASH, 40% male, 72% with type 2 diabetes

    FibroTest Metabolic

  35. The product of triglycerides and glucose as biomarker for screening simple steatosis and NASH in asymptomatic women.

    Simental-Mendía LE et al. · Ann Hepatol · 2016 Match 72

    …08 for simple steatosis, and 2.80 and 0.18 for NASH…

    NashTest SteatoTest Metabolic

  36. The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.

    Netanel C et al. · Am J Surg · 2021 Match 71

    …kg/m^2^. Concomitantly, significant improvements in triglycerides, ALT, diabetes markers and…

    FibroTest NashTest SteatoTest Metabolic

  37. Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.

    Lassailly G et al. · Eur J Gastroenterol Hepatol · 2011 Match 70

    ### Background Liver biopsy is considered as the gold standard for assessing nonalcoholic…

    FibroTest NashTest SteatoTest Metabolic

  38. Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.

    Pais R et al. · Eur J Intern Med · 2015 Match 69

    2.3±1.8; 3±2.6 and 3.8±2.7…

    FibroTest SteatoTest HBV HCV +1

  39. Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.

    Zelber-Sagi S et al. · World J Gastroenterol · 2013 Match 68

    …Most subjects (84.2%) with FLI < 60 had S0 and none had…

    SteatoTest Metabolic

  40. Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.

    Zelber-Sagi S et al. · Hepatology · 2008 Match 67

    ### Unlabelled Physical activity (PA) is commonly recommended for nonalchoholic fatty liver disease…

    SteatoTest Metabolic

  41. Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.

    Harris R et al. · Lancet Gastroenterol Hepatol · 2017 Match 67

    …hazardous alcohol use, or type 2 diabetes, reported higher prevalence of advanced…

    FibroTest Other

  42. Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.

    Chiou YL et al. · J Am Coll Nutr · 2021 Match 66

    …Complicated syndromes often accompanied by obesity and diabetes makes no standard treatment…

    ActiTest FibroTest SteatoTest Metabolic

  43. HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.

    Steininger K et al. · J Viral Hepat · 2017 Match 65

    Acute hepatitis C virus infection remains a major health concern in human…

    FibroTest HCV HIV

  44. FibroMAX: towards a new universal biomarker of liver disease?

    Morra R et al. · Expert Rev Mol Diagn · 2007 Match 64

    Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…

    ActiTest AshTest FibroTest NashTest +7

  45. Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.

    Sebastiani G et al. · World J Gastroenterol · 2007 Match 63

    …diagnose significant fibrosis (F > or = 2 by METAVIR) and cirrhosis (F4 by…

    FibroTest HBV

  46. Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.

    Poynard T et al. · Aliment Pharmacol Ther · 2023 Match 62

    FibroTest-T2D NashTest-T2D SteatoTest-T2D Metabolic

  47. Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.

    Alric L et al. · Transpl Int · 2009 Match 62

    To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…

    FibroTest HBV HCV

  48. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

    Poynard T et al. · Diagnostics (Basel) · 2025 Match 61

    **Background/Objectives:** Bariatric surgery (BS), drugs approved for type-2-diabetes (T2D…

    FibroTest-T2D Metabolic

  49. Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease.

    White DL et al. · J Clin Gastroenterol · 2012 Match 60

    …Americans [odds ratio (OR)(adj)=2.08; 95% confidence interval (CI),0…

    ActiTest FibroTest HCV

  50. Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.

    Canbakan M et al. · Nephron Clin Pract · 2011 Match 59

    …Eleven of the 33 patients had scores ≤0.2, 6 had significant…

    FibroTest HCV

  51. Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.

    López Tórrez SM et al. · Front Nutr · 2024 Match 58

    …aspartate aminotransferase/alanine aminotransferase ratio, diabetes score (BARD score), FibroMeter, FibroTest, enhanced…

    FibroTest Metabolic

  52. EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication

    European Association for Study of Liver et al. · J Hepatol · 2015 Match 57

    FibroTest Alcohol HBV HCV +3

  53. Silymarin in non alcoholic fatty liver disease.

    Cacciapuoti F et al. · World J Hepatol · 2013 Match 56

    ### Aim This study was undertaken to evaluate the hepatic effects of silybum…

    SteatoTest Metabolic

  54. Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication

    AASLD/IDSA HCV Guidance Panel · Hepatology · 2015 Match 56

    ActiTest FibroTest HCV

  55. EASL Clinical Practice Guidelines: management of hepatitis C virus infection.

    European Association for the Study of the Liver · J Hepatol · 2011 Match 55

    ActiTest FibroTest HCV

  56. An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication

    Myers RP et al. · Can J Gastroenterol · 2012 Match 54

    Chronic hepatitis C remains a significant medical and economic burden in Canada…

    FibroTest HCV

  57. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

    Terrault NA et al. · Hepatology · 2018 Match 53

    ActiTest FibroTest HBV

  58. Guidelines for the screening, care and treatment of persons with hepatitis C infection Key publication

    Match 52

    FibroTest HCV

  59. Ministère des Affaires Sociales et de la Santé Key publication

    Match 51

    FibroTest HBV HCV

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