Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
41/433
Matches for
“FIB4, Fibrosis-4”
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B.
…APRI [0.07 (0.02-0.13)] and FIB4 vs. APRI [0…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…An algorithm using the Fib4 for identifying patients with F2 stage or…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…Significant (F2-4) and advanced fibrosis (F3,4) were defined using Kleiner…
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Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
…blood fibrosis tests (Nonalcoholic Fatty Liver Disease Fibrosis Score, FIB4, Fibrotest, FibroMeter…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…used NITs (Fibrosis 4 test [FIB4], Enhanced Liver Fibrosis [ELF] test, FibroScan…
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Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
…results (ISHAK fibrosis score). The mean scores of FibroTest, FIB4, APRI, and…
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…and blood tests targeting fibrosis (APRI, FIB4, Fibrotest, Hepascore, FibroMeter) or cirrhosis…
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Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD.
…four noninvasive tests (NITs; Fibrosis-4 [FIB4], vibration controlled transient elastography [VCTE…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference.
…Contemporaneous biopsies were blindly assessed using the new steatosis, activity and fibrosis…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
FibroTest has been validated as a biomarker of fibrosis in patients with…
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Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease.
…to determine the stage of fibrosis in non-alcoholic fatty liver disease…
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Liver fibrosis markers in alcoholic liver disease.
…The evaluation of the degree of liver fibrosis is of great value…
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Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference.
…with significant inflammatory activity or fibrosis (A2orF2) were missed by the current…
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Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease.
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External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B.
…glutamyl transpeptidase), a marker of fibrosis (alpha2-macroglobulin), and alpha-fetoprotein, a…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV.
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…liver fibrosis (0-27·9%) and cirrhosis (2·4-4·0%) than…
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.
…In a post hoc analysis the FibroTest outperformed VCTE by 4.1…
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Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.
…AUROCs for advanced fibrosis (F3/4) were, respectively, 0.831±0.019…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV.
…Patients were followed for a median of 5.7 (IQR 4.2…
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…elastography (Fibroscan™) to assess liver fibrosis, vs. liver biopsy, in untreated patients…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…prospectively assessed fibrosis, with liver stiffness, FibroTest, APRI, FIB-4 and liver…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease.
…Currently, although several non-invasive fibrosis markers have been suggested as alternatives…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication
…As waiting for the perfect biomarker for the diagnosis of advanced fibrosis…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
…VCTE), and the fibrosis-4 index (FIB-4) and two activity biomarkers…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.
…Meta-analysis of the percentage of fibrosis progression per year (pFPy) was…
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Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
…4, Fibrotest, Fibrometre, and Fibroscan. Elastometric thresholds were identified for significant fibrosis…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…2, 3, 4, 5 or 6 and advanced fibrosis or compensated cirrhosis.
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.
…the most accurate estimating methods are FibroMeter, FIB-4, NAFLD fibrosis score…
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
…assessed for fibrosis [FibroTest; FibroScan; fibrosis-4 index (FIB-4), aspartate-aminotransferase…
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Impact of steatosis and inflammation definitions on the performance of NASH tests.
…including 15 cases with significant fibrosis. The simplified definition increased the κ…
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Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
…For the diagnosis of all fibrosis stages as presumed by FT, the…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…Thresholds defined for each stage of fibrosis were close to those previously…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…8-4.4]). Of the 138 responders with advanced fibrosis, only 31…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…FIB-4 for any fibrosis, FibroMeter for significant fibrosis, ELF for advanced…
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[Prognosis assessment of alcoholic liver disease: how and why?].
Alcoholic liver disease (ALD) causes more than 5000 deaths per year in…
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Assessment of liver fibrosis: noninvasive means.
…For FibroTest, the mean diagnostic value for the diagnosis of advanced fibrosis…
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Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
…FibroTest-T2D predicts fibrosis regression after BS. Applying 3M and adjustments could…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection.
…The detection and quantification of liver fibrosis is a key factor for…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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