Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
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“SVR, sustained virological response”
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Management of the patient with SVR. Review
…drugs, achievement of a sustained virological response (SVR) is achievable in ⩾90…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
…IP-10 levels on sustained virological response (SVR) and the association of…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
…In conclusion, whatever the virological response, treatment for HCV infection is associated…
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…occur in patients with sustained virologic response (SVR) with residual fibrosis. Due…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
…There were 29 (25%) patients who achieved sustained virological response (SVR). ### Results…
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
…cases, resulting in a sustained virological response(SVR) rate of 70.7…
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
…lower in patients with sustained virological response than in nonresponders, and were…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
…Specifically, direct-acting antiviral agents with dramatically improved rates of virological clearance…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…Sustained virological response 12 weeks after treatment was determined. ### Results Forty-four…
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
…or not they attained sustained virologic response (SVR). Scores from four biomarker…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV.
…3%) patients had a sustained virological response. There were 137 cases of…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.
…In patients with advanced fibrosis, stratified by virological response, there were similar…
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
…Patients with a sustained virological response had lower baseline scores than nonresponders…
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
…Efficacy was assessed by the percentage of patients achieving SVR 12 weeks…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…A sustained virologic response was obtained in 45% of patients>or=65…
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
### Background In the UNITY-3 study, 96% sustained virologic response (SVR12) rate…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.
…In addition, hepatic stiffness may also help to prognosticate treatment response to…
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
…The virological response did not differ between cases and controls. The alanine…
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Guidelines for the screening, care and treatment of persons with hepatitis C infection Key publication
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Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters?
…a factor predicting a poor response to currently available therapies. The timing…
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Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
…Outcomes in a sustained virological response (SVR) negative population and a SVR…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices.
Emerging data indicate that all-oral antiviral treatments for chronic hepatitis C…
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External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B.
### Background And Aims The liver cancer risk test (LCR1-LCR2) is a…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…HCV treatment (9 with sustained virologic response). TE, APRI and Fibrotest did…
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Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.
### Background Assessment of fibrosis progression in chronic liver disease relies upon non…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication
FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…
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Ministère des Affaires Sociales et de la Santé Key publication
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