Scientific publications for BioPredictive non-invasive diagnostics

Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies.

Poynard T et al. · Antivir Ther · 2010 Match 100

…Meta-analysis of the percentage of fibrosis progression per year (pFPy) was…

ActiTest FibroTest HBV HCV +1

Changes of non-invasive markers and FibroScan values during HCV treatment.

Vergniol J et al. · J Viral Hepat · 2009 Match 98

…of non-invasive methods for assessment of fibrosis allows serial assessments in…

FibroTest HCV

Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.

Crisan D et al. · Indian J Med Res · 2017 Match 96

### Background & Objectives One of the multiple factors contributing to virological response in…

ActiTest FibroTest SteatoTest HCV

An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication

Myers RP et al. · Can J Gastroenterol · 2012 Match 94

…Specifically, direct-acting antiviral agents with dramatically improved rates of virological clearance…

FibroTest HCV

Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).

Poynard T et al. · J Hepatol · 2014 Match 92

…term dynamics of fibrosis in patients with sustained virological response. ### Methods The…

ActiTest FibroTest HBV

Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.

Poynard T et al. · J Hepatol · 2013 Match 90

…of SVR on the dynamic of fibrosis presumed by FibroTest™. ### Methods In…

FibroTest HCV

EASL Clinical Practice Guidelines: management of hepatitis C virus infection.

European Association for the Study of the Liver · J Hepatol · 2011 Match 87

ActiTest FibroTest HCV

Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.

Zarski JP et al. · Liver Int · 2010 Match 85

…of fibrosis by morphometry and changes in blood markers of fibrosis. ### Results…

ActiTest FibroTest HCV

Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.

Preda CM et al. · Liver Int · 2018 Match 83

### Background Direct antiviral agents (DAA) showed very good results in terms of…

FibroTest HCV

Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness.

Stasi C et al. · World J Gastroenterol · 2016 Match 81

…presence of fibrosis, including the elastometric measure of stiffness, panels of clinical…

FibroTest HCV

Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication

Poynard T et al. · J Viral Hepat · 2009 Match 79

…quantitative estimate of liver fibrosis and necroinflammatory activity in patients with chronic…

ActiTest FibroTest HBV

Biochemical markers of liver fibrosis in patients infected by hepatitis C virus: longitudinal validation in a randomized trial.

Poynard T et al. · J Viral Hepat · 2002 Match 77

…of the fibrosis index score among the 17 sustained virologic responders, from…

FibroTest HCV

Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.

Geri G et al. · J Viral Hepat · 2012 Match 74

…No beneficial effects of RTX were evidenced on liver fibrosis progression, but…

FibroTest Alcohol HBV HCV +1

Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.

Asselah T et al. · Liver Int · 2018 Match 72

…We evaluated the safety and efficacy of sofosbuvir-velpatasvir in patients with…

FibroTest HCV

Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.

Vergniol J et al. · Gastroenterology · 2011 Match 70

…In patients with chronic liver diseases, level of fibrosis predicts liver-related…

FibroTest HCV HIV

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

Terrault NA et al. · Hepatology · 2018 Match 68

ActiTest FibroTest HBV

Management of the patient with SVR. Review

Terrault NA et al. · J Hepatol · 2016 Match 66

…of a sustained virological response (SVR) is achievable in ⩾90% of hepatitis…

FibroTest HCV

Assessment of liver fibrosis: noninvasive means.

Poynard T et al. · Saudi J Gastroenterol · 2008 Match 64

…the first line assessment of fibrosis stage in the four most common…

FibroTest Alcohol HBV HCV +3

Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication

AASLD/IDSA HCV Guidance Panel · Hepatology · 2015 Match 61

ActiTest FibroTest HCV

Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.

Patel K et al. · Aliment Pharmacol Ther · 2016 Match 59

### Background Assessment of fibrosis progression in chronic liver disease relies upon non…

Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients.

Myers RP et al. · AIDS · 2003 Match 57

…index of biochemical markers for the prediction of fibrosis in patients with…

FibroTest HCV HIV

FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication

Halfon P et al. · Gastroenterol Clin Biol · 2008 Match 55

FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…

FibroTest Alcohol HBV HCV +2

Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection

Match 53

FibroTest HBV