Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
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“Men having sex with men”
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American Association for the Study of the Liver
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
…virus(HIV)-infected men who have sex with men (MSM). New direct…
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Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.
…HBV-G infected patients were exclusively from Western Europe with homosexual intercourses…
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Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
…For the first time, obesity was associated with eF before T2D (_p…
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Guidelines for the screening, care and treatment of persons with hepatitis C infection Key publication
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Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.
### Objectives The SteatoTest, fatty liver index (FLI) and hepatic steatosis index (HSI…
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Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups.
…ranging from 13 years in men infected after the age of 40…
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Finasteride and methadone use and risk of advanced hepatitis C related liver disease.
…There were non-significant decreased risks with finasteride use (OR(adj advanced…
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…against advanced hepatic fibrosis in men with chronic HCV infection. Additional research…
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Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
…In 111 COPD patients, 75% exhibited liver damage with a prevalence of…
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Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
…Histological diagnoses used Kleiner et al's scoring system, with 3 classes…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…Only transient elastography and FibroTest were compared with histological endpoints. The prevalence…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…FT), in patients with NAFLD. ### Methods 170 patients with suspected NAFLD were…
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
…low fibrosis with no progression (29.6%, profile A), low fibrosis with…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
…Endocrinologists and those caring for patients with type 2 diabetes mellitus (T2DM…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Liver biopsy may be used in patients with suspected ALD to confirm…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices.
…Coinciding with new treatment options are novel methodologies for disease screening and…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
Changes in the liver and bile ducts observed in patients diagnosed with…
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
…In the clinical setting, biomarkers may discriminate between patients with NASH or…
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Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
…Subjects with presumed advanced fibrosis (FibroTest greater than 0.48) were re…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.
…In DIACART, the FibroTest® score was positively correlated with CACS in univariate…
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The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
…Three hundred and ninety patients with chronic liver disease of miscellaneous causes…
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Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
…The FLI was very strongly correlated with SteatoTest (r = 0.91, P…
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
…disease, with a potential for high diagnostic accuracy in Asians with chronic…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…206 chronic hepatitis C patients with liver biopsy performed before starting antiviral…
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Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
…Patients with an LSM range between 7 and 13 kPa underwent liver…
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Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.
…of fibrotic changes in patients with progressive chronic liver disease. Our aim…
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Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…89.5% with predictive value (PV) and 87.5% with sensitivity/specificity…
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Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…Children present severe fatty liver disease with early cirrhosis. Before enzyme replacement…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Subjects were followed biannually, with a second biopsy offered to those eligible…
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Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
…We aimed to compare the accuracy of 6 NITs between patients with…
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
…The association of Coopscore© with Fibroscan™ increases its predictive value.
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…0.751-0.868)] with a significant increase for FIB4: 0.879…
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Ministère des Affaires Sociales et de la Santé Key publication
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